Most liver diseases, including acute liver injury, drug-induced liver injury, viral hepatitis,
metabolic liver diseases, and end-stage liver diseases, are strongly linked with hormonal …

The liver performs a multitude of bodily functions, whilst retaining the ability to regenerate
damaged tissue. In this review, we discuss sex steroid biology, regulation of mammalian …

Acute and chronic hepatic damages are caused by xenobiotics or different diseases
affecting the liver, characterized by different etiologies and pathological features. It has been …

Studies have shown gender dimorphic response of the liver for various hepatic stresses
including ischemia/reperfusion, hemorrhagic shock-resuscitation, hepatectomy, liver …

The striking gender disparity observed in the incidence of hepatocellular carcinoma (HCC)
suggests an important role of sex hormones in HCC pathogenesis. Though the studies …

Gender medicine focuses on the patho-physiological, clinical, prevention and treatment
differences in diseases that are equally represented in men and women. The purpose of …

Drug-induced liver injury (DILI) remains a clinical challenge due to the poorly predictable
outcomes. Accordingly, considerable efforts have been devoted to unravel the risk factors …

The liver is one of the most essential organs involved in the regulation of energy
homeostasis. Hepatic steatosis, a major manifestation of metabolic syndrome, is associated …

Background Estrogens regulate sexual function and also have a significant role in various
pathophysiological processes. Estrogens have a non-reproductive role as the modulators of …

The immune system responds differently in women and in men. Generally speaking, adult
females show stronger innate and adaptive immune responses than males. This results in …