Mechanisms of endothelial cell migration

UR Michaelis - Cellular and molecular life sciences, 2014 - Springer
Cell migration plays a central role in a variety of physiological and pathological processes
during our whole life. Cellular movement is a complex, tightly regulated multistep process …

Endothelial cell migration during angiogenesis

L Lamalice, F Le Boeuf, J Huot - Circulation research, 2007 - Am Heart Assoc
Endothelial cell migration is essential to angiogenesis. This motile process is directionally
regulated by chemotactic, haptotactic, and mechanotactic stimuli and further involves …

Signalling mechanisms in the regulation of vascular cell migration

H Abedi, I Zachary - Cardiovascular research, 1995 - academic.oup.com
The migration of arterial vascular smooth muscle cells (VSMC) is thought to play a central
role in atherogenesis and restenosis. The migration of several other cell types, including …

[HTML][HTML] Endothelial cells on the move: dynamics in vascular morphogenesis and disease

CG Fonseca, P Barbacena, CA Franco - Vascular Biology, 2020 - vb.bioscientifica.com
The vascular system is a hierarchically organized network of blood vessels that play crucial
roles in embryogenesis, homeostasis and disease. Blood vessels are built by endothelial …

Mechanotransduction in endothelial cell migration

S Li, NF Huang, S Hsu - Journal of cellular biochemistry, 2005 - Wiley Online Library
The migration of endothelial cells (ECs) plays an important role in vascular remodeling and
regeneration. EC migration can be regulated by different mechanisms such as chemotaxis …

[HTML][HTML] Endothelial barrier function and leukocyte transmigration in atherosclerosis

TJ Sluiter, JD van Buul, S Huveneers, PHA Quax… - Biomedicines, 2021 - mdpi.com
The vascular endothelium is a highly specialized barrier that controls passage of fluids and
migration of cells from the lumen into the vessel wall. Endothelial cells assist leukocytes to …

[HTML][HTML] Cell migration: a physically integrated molecular process

DA Lauffenburger, AF Horwitz - cell, 1996 - cell.com
Cell migration plays a central role in a wide variety of biological phenomena. In
embryogenesis, cellular migrations are a recurring theme in important morphogenic …

A biophysical view of the interplay between mechanical forces and signaling pathways during transendothelial cell migration

KM Stroka, H Aranda‐Espinoza - The FEBS journal, 2010 - Wiley Online Library
The vascular endothelium is exposed to an array of physical forces, including shear stress
via blood flow, contact with other cells such as neighboring endothelial cells and leukocytes …

[HTML][HTML] Flow goes forward and cells step backward: endothelial migration

HW Lee, JH Shin, M Simons - Experimental & Molecular Medicine, 2022 - nature.com
Systemic and pulmonary circulations constitute a complex organ that serves multiple
important biological functions. Consequently, any pathological processing affecting the …

Neutrophil transendothelial migration hotspots–mechanisms and implications

MLB Grönloh, JJG Arts, JD van Buul - Journal of cell science, 2021 - journals.biologists.com
During inflammation, leukocytes circulating in the blood stream exit the vasculature in a
process called leukocyte transendothelial migration (TEM). The current paradigm of this …