Study Of (NF-κb) Gene Expression As A Biomarker For Development Of Cardiovascular Disease In Type 2 Diabetes.

AMH Al-Husseini - Journal of Pharmaceutical Negative …, 2022 - search.ebscohost.com
The purpose of this research is to see if there is a link between diabetes type 2
complications and the level of nuclear factor kappa B (NF-κB) overexpression. Ninety blood …

Association of NF-κB1 Gene Polymorphism with Diabetic Kidney Disease Risk in Type 2 Diabetics

SH Mohamed, AA Kamel, HM Allam… - Zagazig University …, 2023 - zumj.journals.ekb.eg
Background: Diabetic kidney disease (DKD) is the most common cause of end-stage renal
failure and a significant contributor to cardiovascular mortality in diabetics. The development …

NFκB polymorphisms and susceptibility to type 1 diabetes

DM Hegazy, DA O'Reilly, BM Yang, AD Hodgkinson… - Genes & …, 2001 - nature.com
Nuclear factor kappa B (NFκB) is an important transcription factor that is involved in the
response to oxidative stress and inflammation. Recent studies suggest that it may be …

Association of serum NF-κB levels with peripheral neuropathy in type 2 diabetes mellitus patients: a pilot study

N Priyadarsini, M Ramachandran… - … Molecular Biology and …, 2024 - degruyter.com
Objectives Hyperglycaemia-induced inflammation plays a vital role in the development of
diabetic peripheral neuropathy (DPN). Recent evidences had reported the involvement of …

Protective effect of acetylcysteine, histidine, and their combination against diabetes vascular complications in type-2 diabetic rats via reducing NF-kβ pathway …

S Mahdavifard, M Nakhjavani - Journal of Diabetes & Metabolic Disorders, 2022 - Springer
Purpose The nuclear factor-kappa B (NF-κB) signaling participates in diabetes
complications. Therefore, the reduction of NF-κB signaling may be a goal to prevent or …

[HTML][HTML] Nuclear Factor-κB is a prime candidate for the diagnosis and control of inflammatory cardiovascular disease

A Matsumori - European Cardiology Review, 2023 - ncbi.nlm.nih.gov
Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is responsible for the
regulation of genes involved in inflammation and immune responses. NF-κB may play an …

[HTML][HTML] NF-κβ: a potential target in the management of vascular complications of diabetes

SV Suryavanshi, YA Kulkarni - Frontiers in pharmacology, 2017 - frontiersin.org
Diabetes is a metabolic disorder affecting large percentage of population worldwide. NF-κβ
plays key role in pathogenesis of vascular complications of diabetes. Persistent …

[HTML][HTML] NF-κB gene expression in peripheral blood and urine in early diagnosis of diabetic nephropathy–a liquid biopsy approach

GL da Veiga, MGDN Raffo, BCA Alves, MR Bacci… - Urine, 2019 - Elsevier
Diabetic nephropathy (DN) is a pathological condition that affects diabetic patients around
the world, and it is the main cause of chronic kidney diseases. It is known that the …

Role of NF-κB in the pathogenesis of diabetes and its associated complications

S Patel, D Santani - Pharmacological reports, 2009 - Springer
The nuclear factor-κB (NF-κB) family is comprised of DNA-binding protein factors that are
required for the transcription of most proinflammatory molecules, including adhesion …

Glucose control with insulin results in reduction of NF‐κB‐binding activity in mononuclear blood cells of patients with recently manifested type 1 diabetes

S Schiekofer, G Galasso, M Andrassy… - Diabetes, obesity …, 2006 - Wiley Online Library
Aim: Chronic elevated blood glucose levels are associated with the formation of advanced
glycation endproducts (AGEs). Hyperglycaemia and AGEs have been shown to induce …