Interactions between Borrelia burgdorferi and ticks

C Kurokawa, GE Lynn, JHF Pedra, U Pal… - Nature Reviews …, 2020 - nature.com
Borrelia burgdorferi is the causative agent of Lyme disease and is transmitted to vertebrate
hosts by Ixodes spp. ticks. The spirochaete relies heavily on its arthropod host for basic …

Tick–host–pathogen interactions in Lyme borreliosis

JWR Hovius, AP van Dam, E Fikrig - Trends in parasitology, 2007 - cell.com
Borrelia burgdorferi, the spirochetal agent of Lyme borreliosis, is predominantly transmitted
by Ixodes ticks. Spirochetes have developed many strategies to adapt to the different …

Borrelia Burgdorferi and Tick Proteins Supporting Pathogen Persistence in the Vector

F Kung, J Anguita, U Pal - Future microbiology, 2013 - Taylor & Francis
Borrelia burgdorferi, a pathogen transmitted by Ixodes ticks, is responsible for a prevalent
illness known as Lyme disease, and a vaccine for human use is unavailable. Recently …

Of ticks, mice and men: understanding the dual-host lifestyle of Lyme disease spirochaetes

JD Radolf, MJ Caimano, B Stevenson… - Nature reviews …, 2012 - nature.com
In little more than 30 years, Lyme disease, which is caused by the spirochaete Borrelia
burgdorferi, has risen from relative obscurity to become a global public health problem and a …

Modulation of the tick gut milieu by a secreted tick protein favors Borrelia burgdorferi colonization

S Narasimhan, TJ Schuijt, NM Abraham… - Nature …, 2017 - nature.com
Abstract The Lyme disease agent, Borrelia burgdorferi, colonizes the gut of the tick Ixodes
scapularis, which transmits the pathogen to vertebrate hosts including humans. Here we …

[HTML][HTML] Adaptation of Borrelia burgdorferi in the vector and vertebrate host

U Pal, E Fikrig - Microbes and infection, 2003 - Elsevier
Borrelia burgdorferi sensu lato is the causative agent of Lyme disease, which afflicts both
humans and some domestic animals. B. burgdorferi, a highly evolved extracellular …

Interaction of the Lyme disease spirochete with its tick vector

MJ Caimano, D Drecktrah, F Kung… - Cellular …, 2016 - Wiley Online Library
Borrelia burgdorferi, the causative agent of Lyme disease (along with closely related
genospecies), is in the deeply branching spirochete phylum. The bacterium is maintained in …

[HTML][HTML] Borrelia burgdorferi–traveling incognito?

E Fikrig, S Narasimhan - Microbes and infection, 2006 - Elsevier
We outline in this review how Borrelia burgdorferi, the causative agent of Lyme disease,
moves from the tick to the vertebrate host, and what molecules are potentially involved in this …

The role of Borrelia burgdorferi outer surface proteins

MR Kenedy, TR Lenhart… - FEMS Immunology & …, 2012 - academic.oup.com
Human pathogenic spirochetes causing Lyme disease belong to the Borrelia burgdorferi
sensu lato complex. Borrelia burgdorferi organisms are extracellular pathogens transmitted …

Host association of Borrelia burgdorferi sensu lato–the key role of host complement

K Kurtenbach, S De Michelis, S Etti, SM Schäfer… - Trends in …, 2002 - cell.com
Borrelia burgdorferi sensu lato (sl), the tick-borne agent of Lyme borreliosis, is a bacterial
species complex comprising 11 genospecies. Here, we discuss whether the delineation of …