Current clinical strategies of pancreatic cancer treatment and open molecular questions

M Brunner, Z Wu, C Krautz, C Pilarsky… - International journal of …, 2019 - mdpi.com
Pancreatic cancer is one of the most lethal malignancies and is associated with a poor
prognosis. Surgery is considered the only potential curative treatment for pancreatic cancer …

Opportunities and challenges in targeted therapy and immunotherapy for pancreatic cancer

D Cao, Q Song, J Li, Y Jiang, Z Wang… - Expert reviews in …, 2021 - cambridge.org
Pancreatic cancer is one of the most malignant tumours with a poor prognosis. In recent
years, the incidence of pancreatic cancer is on the rise. Traditional chemotherapy and …

[HTML][HTML] Curing pancreatic cancer

B Traub, KH Link, M Kornmann - Seminars in cancer biology, 2021 - Elsevier
The distinct biology of pancreatic cancer with aggressive and early invasive tumor cells, a
tumor promoting microenvironment, late diagnosis, and high therapy resistance poses major …

[HTML][HTML] Pancreatic cancer from molecular pathways to treatment opinion

M Karanikas, A Esempidis, ZTM Chasan… - Journal of …, 2016 - ncbi.nlm.nih.gov
Pancreatic cancer is considered one of the most lethal malignances. It has been observed
that the five year survival rate is less than 5%. Early diagnosis, understanding the risk factors …

An update on treatment options for pancreatic adenocarcinoma

A Lambert, L Schwarz, I Borbath… - … in medical oncology, 2019 - journals.sagepub.com
Pancreatic cancer is one of the most lethal solid organ tumors. Due to the rising incidence,
late diagnosis, and limited treatment options, it is expected to be the second leading cause …

Pancreatic cancer: role of the immune system in cancer progression and vaccine-based immunotherapy

A Amedei, E Niccolai, D Prisco - Human vaccines & …, 2014 - Taylor & Francis
Pancreatic cancer (PC) is the 5th leading cause of cancer related death in the developed
world with more than 260,000 deaths annually worldwide and with a dismal 5-year survival …

Pancreatic cancer: current and future treatment strategies

K Pliarchopoulou, D Pectasides - Cancer treatment reviews, 2009 - Elsevier
Pancreatic cancer is a disease with a high mortality rate and short survival, as a result of the
high incidence of metastatic disease at diagnosis, the fulminant clinical course and the lack …

Pancreatic cancer: optimizing treatment options, new, and emerging targeted therapies

EG Chiorean, AL Coveler - Drug design, development and therapy, 2015 - Taylor & Francis
Pancreatic cancer is the fourth leading cause of cancer death in the US and is expected to
become the second leading cause of cancer-related deaths in the next decade. Despite 5 …

Pancreatic cancer: challenges and opportunities

H Zhu, T Li, Y Du, M Li - BMC medicine, 2018 - Springer
Pancreatic cancer is the fourth leading cause of cancer-related death in the United States,
with increasing incidence. The mortality rate of pancreatic cancer is rising rapidly, and is …

[HTML][HTML] New targeted therapies in pancreatic cancer

A Seicean, L Petrusel, R Seicean - World journal of …, 2015 - ncbi.nlm.nih.gov
Patients with pancreatic cancer have a poor prognosis with a median survival of 4-6 mo and
a 5-year survival of less than 5%. Despite therapy with gemcitabine, patient survival does …