Adeno-associated viruses (AAV) are ubiquitous in the human population (> 90% of adults
are seropositive) but have never been implicated as the cause of any disease. They were …

Publisher Summary The adeno-associated viruses (AAV) are defective parvoviruses that
require coinfection with an adenovirus for a productive infection. In many ways AAV is a …

A clone of human cells (Detroit 6) latently infected by adeno-associated virus (AAV) has
been characterized with regard to the status of the viral DNA. In both early (9 to 10) and late …

The adenovirus-associated viruses (AAV) are a newly recognized group of defective viruses
that are capable of multiplying only in cell cultures infected with an adenovirus. Their natural …

Detroit 6 cells exposed to 250 TCID 50/cell of adeno-associated virus (AAV)-2 retained the
ability to produce AAV antigens and infectious virus upon subsequent exposure to helper …

The preliminary data shown in this rcport suggest, t) hat'A4V part, iclcs replicate within t, he
nuclei of doubly infected cells, in many instances as readily recognized units. This …

AAV found in simian adenovirus type 15 preparations has been reported to contain double-
stranded DNA on the basis of acridine orange staining. 1 However, AAV nucleic acid has not …

AAV type 1 has been shown to replicate in several species of cell cultures with the aid of
certain helper adenoviruses from man, monkey, mouse, and dog. However, during the …

We constructed insertion and deletion mutants with mutations within the adeno-associated
virus (AAV) sequences of the infectious recombinant plasmid pSM620. Studies of these …

We have cloned intact duplex adeno-associated virus (AAV) DNA into the bacterial plasmid
pBR322. The AAV genome could be rescued from the recombinant plasmid by transfection …