Extensive research has yielded crucial insights into the mechanism of neurotransmitter
release, and working models for the functions of key proteins involved in release. The …

Research for three decades and major recent advances have provided crucial insights into
how neurotransmitters are released by Ca2+‐triggered synaptic vesicle exocytosis, leading …

Major recent advances and previous data have led to a plausible model of how key proteins
mediate neurotransmitter release. In this model, the soluble N-ethylmaleimide-sensitive …

The core of the neurotransmitter release machinery is formed by SNARE complexes, which
bring the vesicle and plasma membranes together and are key for fusion, and by Munc18-1 …

This review summarizes current knowledge of synaptic proteins that are central to synaptic
vesicle fusion in presynaptic active zones, including SNAREs (s oluble N-ethylmaleimide …

The release of neurotransmitters by Ca2+-triggered synaptic vesicle exocytosis is an
exquisitely regulated process that is fundamental for interneuronal communication. This …

The arrival of a nerve impulse at a nerve terminal leads to the opening of voltage-gated
Ca2+ channels and a rapid influx of Ca2+. The increase in Ca2+ concentration at the active …

The core of the membrane fusion machinery that governs neurotransmitter release includes
the SNARE proteins syntaxin-1, SNAP-25 and synaptobrevin, which form a tight “SNARE …

The SM (Sec1/Munc18-like) protein Munc18-1 and the soluble N-ethylmaleimide-sensitive
factor attachment protein (SNAP) receptor (SNARE) proteins syntaxin-1, SNAP-25, and …

The three key players in the exocytotic release of neurotransmitters from synaptic vesicles
are the SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptor) …