Gentiopicroside prevents interleukin-1 beta induced inflammation response in rat articular chondrocyte

L Zhao, J Ye, G Wu, X Peng, P Xia, Y Ren - Journal of Ethnopharmacology, 2015 - Elsevier
Abstract Ethnopharmacological relevance In traditional Chinese medicine, Gentiana
macrophylla Pall have been prescribed for the treatment of pain and inflammatory …

Gentiopicroside attenuates collagen-induced arthritis in mice via modulating the CD147/p38/NF-κB pathway

N Jia, H Ma, T Zhang, L Wang, J Cui, Y Zha… - International …, 2022 - Elsevier
Gentiopicroside (GEN) is a secoiridoid glycosides isolated from a traditional Chinese
medicine Gentiana macrophylla Pall.. It exhibits potential activities in the treatment of …

Iridoid glycosides from the flowers of Gentiana macrophylla Pall. ameliorate collagen-induced arthritis in rats

N Jia, W Chu, Y Li, L Ding, J Duan, J Cui, S Cao… - Journal of …, 2016 - Elsevier
Abstract Background The flowers of Gentiana macrophylla have been usually applied to
cure the joint inflammation and rheumatoid arthritis in Traditional Chinese Medicine …

[HTML][HTML] Eriodictyol inhibits IL-1β-induced inflammatory response in human osteoarthritis chondrocytes

Y Wang, Y Chen, Y Chen, B Zhou, X Shan… - Biomedicine & …, 2018 - Elsevier
Osteoarthritis (OA) is a degenerative disease of joints, which is closely associated with
cartilage degradation. Eriodictyol, a natural flavonoid compound, has been reported to have …

Comparative anti-arthritic investigation of iridoid glycosides and crocetin derivatives from Gardenia jasminoides Ellis in Freund's complete adjuvant-induced arthritis in …

Y Hu, X Liu, Q Xia, T Yin, C Bai, Z Wang, L Du, X Li… - Phytomedicine, 2019 - Elsevier
Background Discovering novel compounds with higher activities is a key aim of natural
products research. Gardenia jasminoides Ellis is a herb with anti-inflammatory properties …

Antiinflammation Effects and Mechanisms Study of Geniposide on Rats with Collagen‐Induced Arthritis

R Wang, H Wu, J Chen, SP Li, L Dai… - Phytotherapy …, 2017 - Wiley Online Library
Geniposide (GE), an iridoid glycoside compound purified from Gardenia jasminoides Ellis,
has antiinflammatory and other pharmacological effects, but its mechanism of actions on …

Anti-rheumatic properties of gentiopicroside are associated with suppression of ROS-NF-κB-NLRP3 axis in fibroblast-like synoviocytes and NF-κB pathway in adjuvant …

M Wang, H Li, Y Wang, Y Hao, Y Huang… - Frontiers in …, 2020 - frontiersin.org
Rheumatoid arthritis (RA) is among the most prevalent forms of autoimmunity.
Gentiopicroside (Gent) is an iridoid glucoside derived from the Gentiana Macrophylla Pall …

Carvacrol ameliorates inflammatory response in interleukin 1β-stimulated human chondrocytes

YU Xiao, B Li, J Liu, X Ma - Molecular medicine reports, 2018 - spandidos-publications.com
Carvacrol, a monoterpenic phenol present in Origanum vulgare (oregano) and Thymus
vulgaris (thyme), possesses anti‑inflammatory effects; however, little is known about the …

Glytabastan B, a coumestan isolated from Glycine tabacina, alleviated synovial inflammation, osteoclastogenesis and collagen-induced arthritis through inhibiting …

Y Tu, L Tan, T Lu, K Wang, H Wang, B Han… - Biochemical …, 2022 - Elsevier
The roots of Glycine tabacina are used to treat rheumatoid arthritis (RA) and joint infection in
folk medicine. Glytabastan B (GlyB), a newly reported coumestan isolated from this species …

Effect of Phellodendron amurense in protecting human osteoarthritic cartilage and chondrocytes

JH Kim, JE Huh, YH Baek, JD Lee, DY Choi… - Journal of …, 2011 - Elsevier
ETHNOPHARMACOLOGICAL RELEVANCE: Traditional medicine has been widely using
Phellodendron amurense Rupr.(Rutaceae) to treat various inflammatory diseases including …