The arrhythmogenesis of atrial fibrillation is associated with the presence of fibrotic atrial
tissue. Not only fibrosis but also physiological anatomical variability of the atria and the …

In patients with atrial fibrillation, intracardiac electrogram signal amplitude is known to
decrease with increased structural tissue remodeling, referred to as fibrosis. In addition to …

Atrial arrhythmias involving a fibrotic substrate are an important cause of morbidity and
mortality. In many cases, effective treatment of such rhythm disorders is severely hindered by …

Personalized computational cardiac models are emerging as an important tool for studying
cardiac arrhythmia mechanisms, and have the potential to become powerful instruments for …

Introduction: Focal atrial tachycardia is commonly treated by radio frequency ablation with
an acceptable long-term success. Although the location of ectopic foci tends to appear in …

Atrial fibrillation is the most common arrhythmia in humans and is associated with high
morbidity, mortality and health-related expenses. Computational approaches have been …

Background: We hypothesized that computerized morphological analysis of the left atrium
(LA) and pulmonary veins (PVs) via fractal measurements of shape and texture features of …

Aims Paroxysmal atrial fibrillation (PAF) is common, often silent, and can be difficult to
detect. Echocardiographic parameters assessing left atrial (LA) remodelling correlated with …

The mechanisms underlying atrial fibrillation (AF), the most common sustained cardiac
rhythm disturbance, remain elusive. Atrial fibrosis plays an important role in the development …

Atrial fibrosis plays a key role in the initiation and progression of atrial fibrillation (AF). Atrial
fibrosis is typically identified by a peak-to-peak amplitude of bipolar electrograms (b-EGMs) …