Background The effectiveness of surgery versus observation for men with localized prostate
cancer detected by means of prostate-specific antigen (PSA) testing is not known. Methods …

Background Very long-term mortality in men with early prostate cancer treated with surgery
versus observation is uncertain. Objective To determine long-term effects of surgery versus …

Background We previously found no significant differences in mortality between men who
underwent surgery for localized prostate cancer and those who were treated with …

Objective.—To assess the results of radical prostatectomy in men with early prostate cancer.
Design.—Retrospective, nonrandomized, multi-institutional pooled analysis. Setting.—Eight …

Background Radical prostatectomy reduces mortality among men with clinically detected
localized prostate cancer, but evidence from randomized trials with long-term follow-up is …

Background The comparative effectiveness of treatments for prostate cancer that is detected
by prostate-specific antigen (PSA) testing remains uncertain. Methods We compared active …

Context Most newly diagnosed prostate cancers are clinically localized, and major treatment
options include surgery, radiation, or conservative management. Although conservative …

Sometimes the war on cancer should be a cold war, not a hot one. That is the message from
the Prostate Cancer Intervention versus Observation Trial (PIVOT) by Timothy Wilt and …

BACKGROUND: Prostate cancer is the most common noncutaneous malignancy and the
second leading cause of cancer death in men. Ninety percent of men with prostate cancer …

BACKGROUND: Strategies of active surveillance (AS) of low‐risk screen‐detected prostate
cancer have emerged, because the balance between survival outcomes and quality of life …