Machine perfusion of the liver: applications in transplantation and beyond

CDL Ceresa, D Nasralla, JM Pollok… - Nature reviews …, 2022 - nature.com
The shortage of donor livers considered suitable for transplantation has driven the
development of novel methods for organ preservation and reconditioning. Machine …

[HTML][HTML] Machine perfusion of the liver and bioengineering

A Schlegel, H Mergental, C Fondevila, RJ Porte… - Journal of …, 2023 - Elsevier
With the increasing number of accepted candidates on waiting lists worldwide, there is an
urgent need to expand the number and the quality of donor livers. Dynamic preservation …

Evolving trends in machine perfusion for liver transplantation

P Dutkowski, JV Guarrera, J De Jonge… - …, 2019 - gastrojournal.org
The imbalance between grafts available for transplantation and demands has moved the
focus of many investigators on the search for novel strategies to rescue organs, previously …

[HTML][HTML] Ex vivo machine perfusion: current applications and future directions in liver transplantation

J Michelotto, JMGV Gassner, S Moosburner… - … archives of surgery, 2021 - Springer
Background Liver transplantation is the only curative treatment option for end-stage liver
disease; however, its use remains limited due to a shortage of suitable organs. In recent …

[HTML][HTML] Machine perfusion strategies in liver transplantation

A Schlegel, X Muller, P Dutkowski - Hepatobiliary surgery and …, 2019 - ncbi.nlm.nih.gov
Abstract Machine perfusion is a hot topic in liver transplantation and several new perfusion
concepts are currently developed. Prior to introduction into routine clinical practice, however …

Machine perfusion of the liver: past, present and future

D Monbaliu, J Brassil - Current opinion in organ transplantation, 2010 - journals.lww.com
Despite recent substantial improvements, liver preservation by machine perfusion remains
limited and in contrast to the global revival of kidney machine perfusion. However, liver …

Machine perfusion in liver transplantation

RX Sousa Da Silva, A Weber, P Dutkowski… - …, 2022 - Wiley Online Library
Although liver transplantation is a true success story, many patients still die awaiting an
organ. The increasing need for liver grafts therefore remains an unsolved challenge to the …

[HTML][HTML] Normothermic liver machine perfusion as a dynamic platform for regenerative purposes: What does the future have in store for us?

B Lascaris, VE de Meijer, RJ Porte - Journal of Hepatology, 2022 - Elsevier
Liver transplantation has become an immense success; nevertheless, far more recipients
are registered on waiting lists than there are available donor livers for transplantation. High …

Hypo-and normothermic perfusion of the liver: Which way to go?

J Selten, A Schlegel, J de Jonge… - Best practice & research …, 2017 - Elsevier
The demand of donor livers for transplantation exceeds the supply. In an attempt to
maximize the number of potentially usable donor livers, several centers are exploring the …

[HTML][HTML] Machine perfusion of the liver: a review of clinical trials

N Serifis, R Matheson, D Cloonan, CG Rickert… - Frontiers in …, 2021 - frontiersin.org
Although efforts have been made by transplant centers to increase the pool of available
livers by extending the criteria of liver acceptance, this practice creates risks for recipients …