Aptamer-targeted photodynamic platforms for tumor therapy
J Yan, T Gao, Z Lu, J Yin, Y Zhang… - ACS applied materials & …, 2021 - ACS Publications
Achieving controlled and accurate delivery of photosensitizers (PSs) into tumor sites is a
major challenge in conventional photodynamic therapy (PDT). Aptamer is a short …
major challenge in conventional photodynamic therapy (PDT). Aptamer is a short …
Engineering a cell-surface aptamer circuit for targeted and amplified photodynamic cancer therapy
Photodynamic therapy is one of the most promising and noninvasive methods for clinical
treatment of different malignant diseases. Here, we present a novel strategy of designing an …
treatment of different malignant diseases. Here, we present a novel strategy of designing an …
Assembly of aptamer switch probes and photosensitizer on gold nanorods for targeted photothermal and photodynamic cancer therapy
An aptamer switch probe (ASP) linking chlorin e6 (Ce6), a photosensitizer molecule, to the
surface of gold nanorods (AuNRs) was used to target cancer cells for photodynamic therapy …
surface of gold nanorods (AuNRs) was used to target cancer cells for photodynamic therapy …
Tumor microenvironment (TME)-activatable circular aptamer-PEG as an effective hierarchical-targeting molecular medicine for photodynamic therapy
Photodynamic therapy (PDT) is an effective and noninvasive therapeutic strategy employing
light-triggered singlet oxygen (SO) and reactive oxygen species (ROS) to kill lesional cells …
light-triggered singlet oxygen (SO) and reactive oxygen species (ROS) to kill lesional cells …
ATP-activatable photosensitizer enables dual fluorescence imaging and targeted photodynamic therapy of tumor
Targeted delivery of intracellular stimuli-activatable photosensitizers (PSs) into tumor cells to
achieve selective imaging and on-demand photodynamic therapy (PDT) of tumors has …
achieve selective imaging and on-demand photodynamic therapy (PDT) of tumors has …
[HTML][HTML] Cell specific aptamer-photosensitizer conjugates as a molecular tool in photodynamic therapy
P Mallikaratchy, Z Tang, W Tan - ChemMedChem, 2008 - ncbi.nlm.nih.gov
This paper describes the application of a molecular construct of a photosensitizer and an
aptamer for photo-therapeutically targeting tumor cells. The key step in increasing selectivity …
aptamer for photo-therapeutically targeting tumor cells. The key step in increasing selectivity …
Nanomaterials-based photosensitizers and delivery systems for photodynamic cancer therapy
XT Yu, SY Sui, YX He, CH Yu, Q Peng - Biomaterials Advances, 2022 - Elsevier
The increasing cancer morbidity and mortality requires the development of high-efficiency
and low-toxicity anticancer approaches. In recent years, photodynamic therapy (PDT) has …
and low-toxicity anticancer approaches. In recent years, photodynamic therapy (PDT) has …
All‐in‐one phototheranostics: single laser triggers NIR‐II fluorescence/photoacoustic imaging guided photothermal/photodynamic/chemo combination therapy
Q Wang, Y Dai, J Xu, J Cai, X Niu… - Advanced Functional …, 2019 - Wiley Online Library
Abstract Development of single near‐infrared (NIR) laser triggered phototheranostics for
multimodal imaging guided combination therapy is highly desirable but is still a big …
multimodal imaging guided combination therapy is highly desirable but is still a big …
A pH reversibly activatable NIR photothermal/photodynamic-in-one agent integrated with renewable nanoimplants for image-guided precision phototherapy
X Zhao, KC Zhao, LJ Chen, YS Liu, JL Liu, XP Yan - Chemical Science, 2021 - pubs.rsc.org
Phototherapy has great potential to revolutionize conventional therapeutic modalities.
However, most phototherapeutic strategies based on multicomponent therapeutic agents …
However, most phototherapeutic strategies based on multicomponent therapeutic agents …
Development of Sulfonamide‐Functionalized Charge‐Reversal AIE Photosensitizers for Precise Photodynamic Therapy in the Acidic Tumor Microenvironment
Tumor‐targeted photodynamic therapy (PDT) is desirable as it can achieve efficient killing of
tumor cells with no or less harm to normal cells. Herein, a facile molecular engineering …
tumor cells with no or less harm to normal cells. Herein, a facile molecular engineering …