Mitochondrial dysfunction-targeting therapeutics of natural products in Parkinson's disease

T He, X Lin, A Su, Y Zhang, Z Xing, L Mi… - Frontiers in …, 2023 - frontiersin.org
Parkinson's disease (PD), the second most common neurodegenerative disease worldwide,
often occurs in middle-aged and elderly individuals. The pathogenesis of PD is complex and …

Targeting mitochondria by plant secondary metabolites: a promising strategy in combating Parkinson's disease

S Fakhri, S Abdian, SN Zarneshan, EK Akkol… - International journal of …, 2021 - mdpi.com
Parkinson's disease (PD) is one of the most prevalent and debilitating neurodegenerative
conditions, and is currently on the rise. Several dysregulated pathways are behind the …

Amelioration of mitochondrial quality control and proteostasis by natural compounds in Parkinson's disease models

B Cho, T Kim, YJ Huh, J Lee, YI Lee - International journal of molecular …, 2019 - mdpi.com
Parkinson's disease (PD) is a well-known age-related neurodegenerative disorder
associated with longer lifespans and rapidly aging populations. The pathophysiological …

A focus on natural products for preventing and cure of mitochondrial dysfunction in Parkinson's disease

A Mohammadipour - Metabolic Brain Disease, 2022 - Springer
Mitochondria are considered the only source of energy production within cells. This
organelle is vital for neural function and survival by producing energy (adenosine …

Regulation of mitophagy and mitochondrial function: Natural compounds as potential therapeutic strategies for Parkinson's disease

H Liang, Z Ma, W Zhong, J Liu… - Phytotherapy …, 2024 - Wiley Online Library
Mitochondrial damage is associated with the development of Parkinson's disease (PD),
indicating that mitochondrial‐targeted treatments could hold promise as disease‐modifying …

Natural products as pharmacological modulators of mitochondrial dysfunctions for the treatments of Alzheimer's disease: A comprehensive review

X Jin, JL Guo, L Wang, X Zhong, WF Yao, H Gao… - European journal of …, 2021 - Elsevier
Abstracts Alzheimer's disease (AD) is the most common progressive neurodegenerative
disorder characterized by neuronal loss and cognitive impairment that harshly affect the …

[HTML][HTML] The potentiality of natural products and herbal medicine as novel medications for parkinson's disease: a promising therapeutic approach

YJ So, JU Lee, GS Yang, G Yang, SW Kim… - … Journal of Molecular …, 2024 - ncbi.nlm.nih.gov
As the global population ages, the prevalence of Parkinson's disease (PD) is steadily on the
rise. PD demonstrates chronic and progressive characteristics, and many cases can …

The multifaceted roles of natural products in mitochondrial dysfunction

Q Chen, D Ruan, J Shi, D Du, C Bian - Frontiers in Pharmacology, 2023 - frontiersin.org
Mitochondria are the primary source of energy production in cells, supporting the metabolic
demand of tissue. The dysfunctional mitochondria are implicated in various diseases …

Important medicinal herbs in Parkinson's disease pharmacotherapy

S Srivastav, M Fatima, AC Mondal - Biomedicine & Pharmacotherapy, 2017 - Elsevier
Parkinson's disease (PD) is the most common progressive neurodegenerative movement
disorder affecting more than 10 million people worldwide. The characteristic hallmark of PD …

Nutraceuticals in Parkinson's disease

L Hang, AH Basil, KL Lim - NeuroMolecular Medicine, 2016 - Springer
Current pharmacological strategies for Parkinson's disease (PD), the most common
neurological movement disorder worldwide, are predominantly symptom relieving and are …