Combined toxic exposures and human health: biomarkers of exposure and effect

I Silins, J Högberg - International journal of environmental research and …, 2011 - mdpi.com
Procedures for risk assessment of chemical mixtures, combined and cumulative exposures
are under development, but the scientific database needs considerable expansion. In …

Sources of variability in biomarker concentrations

LL Aylward, SM Hays, R Smolders… - Journal of Toxicology …, 2014 - Taylor & Francis
Human biomonitoring has become a primary tool for chemical exposure characterization in
a wide variety of contexts: population monitoring and characterization at a national level …

The use of biomonitoring data in exposure and human health risk assessments

R Albertini, M Bird, N Doerrer, L Needham… - Environmental …, 2006 - ehp.niehs.nih.gov
Biomonitoring uses analytic methods that permit the accurate measurement of low levels of
environmental chemicals in human tissues. However, depending on the intended use …

Toxicoproteomics—the next step in the evolution of environmental biomarkers?

AD Benninghoff - Toxicological Sciences, 2007 - academic.oup.com
The scientific community has become increasingly concerned about the potential adverse
health effects to humans and wildlife resulting from environmental exposure to persistent …

An overview of the current progress, challenges, and prospects of human biomonitoring and exposome studies

MZ Bocato, JP Bianchi Ximenez… - Journal of Toxicology …, 2019 - Taylor & Francis
Human Biomonitoring (HB), the process for determining whether and to what extent
chemical substances penetrated our bodies, serves as a useful tool to quantify human …

Implications of the exposome for exposure science

SM Rappaport - Journal of exposure science & environmental …, 2011 - nature.com
During the 1920s, the forerunners of exposure science collaborated with health
professionals to investigate the causes of occupational diseases. With the birth of US …

[HTML][HTML] Implementation of effect biomarkers in human biomonitoring studies: A systematic approach synergizing toxicological and epidemiological knowledge

A Rodríguez-Carrillo, V Mustieles… - International Journal of …, 2023 - Elsevier
Human biomonitoring (HBM) studies have highlighted widespread daily exposure to
environmental chemicals. Some of these are suspected to contribute to adverse health …

The conceptual basis of the biomarker approach

MH Depledge, JJ Amaral-Mendes, B Daniel… - … and Application in the …, 1993 - Springer
In recent years technical developments have enhanced our ability to detect and quantify
biological changes that occur at the molecular, cellular, and physiological levels following …

Key developments in endocrine disrupter research and human health

KP Phillips, WG Foster - Journal of toxicology and environmental …, 2008 - Taylor & Francis
Environmental etiologies involving exposures to chemicals that mimic endogenous
hormones are proposed for a number of adverse human health effects, including infertility …

Role of biomarkers in monitoring exposures to chemicals: present position, future prospects

WP Watson, A Mutti - Biomarkers, 2004 - Taylor & Francis
Biomarkers are becoming increasingly important in toxicology and human health. Many
research groups are carrying out studies to develop biomarkers of exposure to chemicals …