Complete Freund's adjuvant-free experimental autoimmune encephalomyelitis in Dark Agouti rats is a valuable tool for multiple sclerosis studies

M Lazarević, N Djedovic, S Stanisavljević… - Journal of …, 2021 - Elsevier
Experimental autoimmune encephalomyelitis (EAE) is classically induced with complete
Freund's adjuvant (CFA). The immune response against CFA has a confounding influence …

Protracted, relapsing and demyelinating experimental autoimmune encephalomyelitis in DA rats immunized with syngeneic spinal cord and incomplete Freund's …

JC Lorentzen, S Issazadeh, M Storch… - Journal of …, 1995 - Elsevier
Experimental autoimmune encephalomyelitis (EAE) is a model for multiple sclerosis (MS).
However, MS is a chronic, relapsing and demyelinating disease, whereas EAE in rats is …

Brain inflammation in experimental autoimmune encephalomyelitis induced in Dark Agouti rats with spinal cord homogenate

G Stegnjaić, B Jevtić, M Lazarević, Đ Ignjatović… - Immunology …, 2024 - Elsevier
We have recently characterized experimental autoimmune encephalomyelitis (EAE) induced
in DA rats with spinal cord homogenate without complete Freund's adjuvant (CFA). The main …

Experimental autoimmune encephalomyelitis: An animal model for multiple sclerosis

K Gijbels, S Engelborghs… - Neuroscience Research …, 2000 - Wiley Online Library
The first section reviews the current knowledge about the neuropathology, pathophysiology,
clinical symptomatology, diagnosis and treatment of multiple sclerosis (MS). Where possible …

Induction of experimental autoimmune encephalomyelitis in Dark Agouti rats without adjuvant

S Stosic-Grujicic, Z Ramic… - Clinical & …, 2004 - academic.oup.com
Experimental autoimmune encephalomyelitis (EAE) is a well-recognized model for multiple
sclerosis (MS) in humans. However, adjuvants used with encephalitogens to induce EAE …

[HTML][HTML] Induction of experimental autoimmune encephalomyelitis with recombinant human myelin oligodendrocyte glycoprotein in incomplete Freund's adjuvant in …

KG Haanstra, SA Jagessar, AL Bauchet… - Journal of Neuroimmune …, 2013 - Springer
The experimental autoimmune encephalitis (EAE) model is used for preclinical research into
the pathogenesis of multiple sclerosis (MS), mostly in inbred, specific pathogen free (SPF) …

T cell and antibody responses in remitting–relapsing experimental autoimmune encephalomyelitis in (C57BL/6× SJL) F1 mice

GX Zhang, S Yu, B Gran, J Li, D Calida… - Journal of …, 2004 - Elsevier
To characterize T cell and antibody responses in remitting–relapsing experimental
autoimmune encephalomyelitis (RR-EAE), we compared myelin oligodendrocyte …

[HTML][HTML] Complete Freund's adjuvant as a confounding factor in multiple sclerosis research

M Lazarević, S Stanisavljević, N Nikolovski… - Frontiers in …, 2024 - frontiersin.org
Complete Freund's adjuvant (CFA) is used as a standard adjuvant for the induction of
experimental autoimmune encephalomyelitis (EAE), the most commonly used animal model …

[HTML][HTML] Passive experimental autoimmune encephalomyelitis in C57BL/6 with MOG: evidence of involvement of B cells

F Mannara, T Valente, J Saura, F Graus, A Saiz… - PLoS …, 2012 - journals.plos.org
Experimental autoimmune encephalomyelitis (EAE) is the most relevant animal model to
study demyelinating diseases such as multiple sclerosis. EAE can be induced by active …

Neuroinflammation and B-cell phenotypes in cervical and lumbosacral regions of the spinal cord in experimental autoimmune encephalomyelitis in the absence of …

E Kummari, JM Nichols, EJ Yang… - Neuroimmunomodulation, 2019 - karger.com
Objectives: The active experimental autoimmune encephalomyelitis (EAE) model is often
initiated using myelin oligodendrocyte glycoprotein (MOG) immunization followed by …