Analysis of the different characteristics between omental preadipocytes and differentiated white adipocytes using bioinformatics methods

X Yang, L Li, C Xu, M Pi, C Wang, Y Zhang - Adipocyte, 2022 - Taylor & Francis
Obesity is emerging as an epidemiological issue, being associated with the onset and
progress of various metabolism-related disorders. Obesity is characterized by the white …

[HTML][HTML] Screening and validation of differentially expressed genes in adipose tissue of patients with obesity and type 2 diabetes mellitus

X Tong, C Liu, M Liang, X Ye, Z Deng… - Biomolecules and …, 2024 - ncbi.nlm.nih.gov
White adipose tissue (WAT) plays a pivotal role in the onset of type 2 diabetes mellitus
(T2DM) and obesity. Despite its significance the underlying pathogenesis and key genes …

[HTML][HTML] Differentially expressed genes and enriched signaling pathways in the adipose tissue of obese people

Z Lu, L Meng, Z Sun, X Shi, W Shao, Y Zheng… - Frontiers in …, 2021 - frontiersin.org
As the prevalence of obesity increases, so does the occurrence of obesity-related
complications, such as cardiovascular and cerebrovascular diseases, diabetes, and some …

Bioinformatics analysis of candidate genes and potential therapeutic drugs targeting adipose tissue in obesity

Y Yu, YH Zhang, L Liu, LL Yu, JP Li, J Rao, F Hu… - Adipocyte, 2022 - Taylor & Francis
Obesity is a complex medical condition that affects multiple organs in the body. However, the
underlying mechanisms of obesity, as well as its treatment, are largely unexplored. The …

[HTML][HTML] Investigation into the underlying molecular mechanisms of white adipose tissue through comparative transcriptome analysis of multiple tissues

S Zhang, L Wang, L Zan - Molecular Medicine Reports, 2019 - spandidos-publications.com
Adipose tissue has a primary role in lipid and glucose metabolism as a storage site for fatty
acids, and also functions as an endocrine organ, producing large numbers of hormones and …

[HTML][HTML] Bioinformatics and next-generation data analysis for identification of genes and molecular pathways involved in subjects with diabetes and obesity

P Ganekal, B Vastrad, S Kavatagimath, C Vastrad… - Medicina, 2023 - mdpi.com
Background and Objectives: A subject with diabetes and obesity is a class of the metabolic
disorder. The current investigation aimed to elucidate the potential biomarker and prognostic …

Identification of biomarkers, pathways and potential therapeutic agents for white adipocyte insulin resistance using bioinformatics analysis

Y Zhang, Y Zheng, Y Fu, C Wang - Adipocyte, 2019 - Taylor & Francis
For the better understanding of insulin resistance (IR), the molecular biomarkers in IR white
adipocytes and its potential mechanism, we downloaded two mRNA expression profiles …

[HTML][HTML] Transcriptomic analysis from Normal glucose tolerance to T2D of obese individuals using Bioinformatic tools

K Errafii, S Boujraf, M Chikri - International Journal of Molecular Sciences, 2023 - mdpi.com
Understanding the role of white adipose tissue (WAT) in the occurrence and progression of
metabolic syndrome is of considerable interest; among the metabolic syndromes are obesity …

Identification of major hub genes involved in high-fat diet-induced obese visceral adipose tissue based on bioinformatics approach

Y Jiang, R Zhang, JQ Guo, LL Qian, JJ Ji, Y Wu, ZJ Ji… - Adipocyte, 2023 - Taylor & Francis
High-fat diet (HFD) can cause obesity, inducing dysregulation of the visceral adipose tissue
(VAT). This study aimed to explore potential biological pathways and hub genes involved in …

[HTML][HTML] Identification of potential key genes associated with adipogenesis through integrated analysis of five mouse transcriptome datasets

S Zhang, L Wang, S Li, W Zhang, X Ma… - International Journal of …, 2018 - mdpi.com
Adipose tissue is the most important energy metabolism and secretion organ, and these
functions are conferred during the adipogenesis process. However, the cause and the …