Analysis of the different characteristics between omental preadipocytes and differentiated white adipocytes using bioinformatics methods
X Yang, L Li, C Xu, M Pi, C Wang, Y Zhang - Adipocyte, 2022 - Taylor & Francis
Obesity is emerging as an epidemiological issue, being associated with the onset and
progress of various metabolism-related disorders. Obesity is characterized by the white …
progress of various metabolism-related disorders. Obesity is characterized by the white …
[HTML][HTML] Screening and validation of differentially expressed genes in adipose tissue of patients with obesity and type 2 diabetes mellitus
X Tong, C Liu, M Liang, X Ye, Z Deng… - Biomolecules and …, 2024 - ncbi.nlm.nih.gov
White adipose tissue (WAT) plays a pivotal role in the onset of type 2 diabetes mellitus
(T2DM) and obesity. Despite its significance the underlying pathogenesis and key genes …
(T2DM) and obesity. Despite its significance the underlying pathogenesis and key genes …
[HTML][HTML] Differentially expressed genes and enriched signaling pathways in the adipose tissue of obese people
Z Lu, L Meng, Z Sun, X Shi, W Shao, Y Zheng… - Frontiers in …, 2021 - frontiersin.org
As the prevalence of obesity increases, so does the occurrence of obesity-related
complications, such as cardiovascular and cerebrovascular diseases, diabetes, and some …
complications, such as cardiovascular and cerebrovascular diseases, diabetes, and some …
Bioinformatics analysis of candidate genes and potential therapeutic drugs targeting adipose tissue in obesity
Y Yu, YH Zhang, L Liu, LL Yu, JP Li, J Rao, F Hu… - Adipocyte, 2022 - Taylor & Francis
Obesity is a complex medical condition that affects multiple organs in the body. However, the
underlying mechanisms of obesity, as well as its treatment, are largely unexplored. The …
underlying mechanisms of obesity, as well as its treatment, are largely unexplored. The …
[HTML][HTML] Investigation into the underlying molecular mechanisms of white adipose tissue through comparative transcriptome analysis of multiple tissues
S Zhang, L Wang, L Zan - Molecular Medicine Reports, 2019 - spandidos-publications.com
Adipose tissue has a primary role in lipid and glucose metabolism as a storage site for fatty
acids, and also functions as an endocrine organ, producing large numbers of hormones and …
acids, and also functions as an endocrine organ, producing large numbers of hormones and …
[HTML][HTML] Bioinformatics and next-generation data analysis for identification of genes and molecular pathways involved in subjects with diabetes and obesity
P Ganekal, B Vastrad, S Kavatagimath, C Vastrad… - Medicina, 2023 - mdpi.com
Background and Objectives: A subject with diabetes and obesity is a class of the metabolic
disorder. The current investigation aimed to elucidate the potential biomarker and prognostic …
disorder. The current investigation aimed to elucidate the potential biomarker and prognostic …
Identification of biomarkers, pathways and potential therapeutic agents for white adipocyte insulin resistance using bioinformatics analysis
Y Zhang, Y Zheng, Y Fu, C Wang - Adipocyte, 2019 - Taylor & Francis
For the better understanding of insulin resistance (IR), the molecular biomarkers in IR white
adipocytes and its potential mechanism, we downloaded two mRNA expression profiles …
adipocytes and its potential mechanism, we downloaded two mRNA expression profiles …
[HTML][HTML] Transcriptomic analysis from Normal glucose tolerance to T2D of obese individuals using Bioinformatic tools
Understanding the role of white adipose tissue (WAT) in the occurrence and progression of
metabolic syndrome is of considerable interest; among the metabolic syndromes are obesity …
metabolic syndrome is of considerable interest; among the metabolic syndromes are obesity …
Identification of major hub genes involved in high-fat diet-induced obese visceral adipose tissue based on bioinformatics approach
Y Jiang, R Zhang, JQ Guo, LL Qian, JJ Ji, Y Wu, ZJ Ji… - Adipocyte, 2023 - Taylor & Francis
High-fat diet (HFD) can cause obesity, inducing dysregulation of the visceral adipose tissue
(VAT). This study aimed to explore potential biological pathways and hub genes involved in …
(VAT). This study aimed to explore potential biological pathways and hub genes involved in …
[HTML][HTML] Identification of potential key genes associated with adipogenesis through integrated analysis of five mouse transcriptome datasets
S Zhang, L Wang, S Li, W Zhang, X Ma… - International Journal of …, 2018 - mdpi.com
Adipose tissue is the most important energy metabolism and secretion organ, and these
functions are conferred during the adipogenesis process. However, the cause and the …
functions are conferred during the adipogenesis process. However, the cause and the …