Cognate tRNAs deliver specific amino acids to translating ribosomes according to the
standard genetic code, and three codons with no cognate tRNAs serve as stop codons …

Termination of protein synthesis occurs when a translating ribosome encounters one of
three universally conserved stop codons: UAA, UAG or UGA. Release factors recognize stop …

In termination of protein synthesis, the bacterial release factors RF1 and RF2 bind to the
ribosome through specific recognition of messenger RNA stop codons and trigger hydrolysis …

Mutating the rare A32-U38 nucleotide pair at the top of the anticodon loop of Escherichia coli
tRNAAlaGGC to a more common U32-A38 pair results in a tRNA that performs almost …

The ribosome converts genetic information into protein by selecting aminoacyl tRNAs whose
anticodons base-pair to an mRNA codon. Mutations in the tRNA body can perturb this …

Pseudouridylation of messenger RNA emerges as an abundant modification involved in
gene expression regulation. Pseudouridylation of stop codons in eukaryotic and bacterial …

During transfer RNA (tRNA) selection, a cognate codon: anticodon interaction triggers a
series of events that ultimately results in the acceptance of that tRNA into the ribosome for …

Transfer RNA molecules translate the genetic code by recognizing cognate mRNA codons
during protein synthesis. The anticodon wobble at position 34 and the nucleotide …

From 50 genomes of the three domains of life (7 eukarya, 13 archaea, and 30 bacteria), we
extracted, analyzed, and compared over 4,000 sequences corresponding to cytoplasmic …

The bases at positions 32 and 38 in the tRNA anticodon loop are known to have a specific
conservation depending upon the anticodon triplets. Here we report that evolutionarily …