[HTML][HTML] Animal models of Klebsiella pneumoniae mucosal infections

L Assoni, AJM Couto, B Vieira, B Milani… - Frontiers in …, 2024 - frontiersin.org
Klebsiella pneumoniae is among the most relevant pathogens worldwide, causing high
morbidity and mortality, which is worsened by the increasing rates of antibiotic resistance. It …

[HTML][HTML] From Klebsiella pneumoniae Colonization to Dissemination: An Overview of Studies Implementing Murine Models

L Joseph, T Merciecca, C Forestier, D Balestrino… - Microorganisms, 2021 - mdpi.com
Klebsiella pneumoniae is a Gram-negative pathogen responsible for community-acquired
and nosocomial infections. The strains of this species belong to the opportunistic group …

[HTML][HTML] Evaluating Different Virulence Traits of Klebsiella pneumoniae Using Dictyostelium discoideum and Zebrafish Larvae as Host Models

AE Marcoleta, MA Varas, J Ortiz-Severín… - Frontiers in Cellular …, 2018 - frontiersin.org
Multiresistant and invasive hypervirulent Klebsiella pneumoniae strains have become one of
the most urgent bacterial pathogen threats. Recent analyses revealed a high genomic …

Modelling the gastrointestinal carriage of Klebsiella pneumoniae infections

R Calderon-Gonzalez, A Lee, G Lopez-Campos… - Mbio, 2023 - Am Soc Microbiol
Klebsiella pneumoniae is a leading cause of nosocomial and community acquired
infections, making K. pneumoniae the pathogen that is associated with the second largest …

Identification of Klebsiella pneumoniae virulence determinants using an intranasal infection model

MS Lawlor, J Hsu, PD Rick, VL Miller - Molecular microbiology, 2005 - Wiley Online Library
Klebsiella pneumoniae is a Gram‐negative enterobacterium that has historically been, and
currently remains, a significant cause of human disease. It is a frequent cause of urinary tract …

Animal model to study Klebsiella pneumoniae gastrointestinal colonization and host-to-host transmission

TM Young, AS Bray, RK Nagpal, DL Caudell… - Infection and …, 2020 - Am Soc Microbiol
An important yet poorly understood facet of the life cycle of a successful pathogen is host-to-
host transmission. Hospital-acquired infections (HAI) resulting from the transmission of drug …

Identification of Endogenous Mechanisms That Affect Klebsiella pneumoniae Growth in the Murine Host.

HYF Lau - 2007 - deepblue.lib.umich.edu
Klebsiella pneumoniae is an opportunistic pathogen and a normal component of the host
flora. The aim of this project was to investigate mechanisms that determine mucosal tissue …

[HTML][HTML] Host and microbiota factors that control Klebsiella pneumoniae mucosal colonization in mice

HY Lau, GB Huffnagle, TA Moore - Microbes and infection, 2008 - Elsevier
Klebsiella pneumoniae is both an opportunistic pathogen and a commensal organism. We
have previously reported that K. pneumoniae strain IA565 (KpIA565) is non-pathogenic in a …

Using Klebsiella pneumoniae to Model Acute Lung Inflammation in Mice

DK McDaniel, IC Allen - Mouse Models of Innate Immunity: Methods and …, 2019 - Springer
Lung infections caused by bacteria can induce a spectrum of immune responses, which is in
part determined by the level of exposure and the degree of the host response. The host …

[HTML][HTML] Zebrafish and Galleria mellonella: models to identify the subsequent infection and evaluate the immunological differences in different Klebsiella pneumoniae …

X Zhang, Y Zhao, Q Wu, J Lin, R Fang, W Bi… - Frontiers in …, 2019 - frontiersin.org
The intestine is the main reservoir of bacterial pathogens in most organisms. Klebsiella
pneumoniae is an important opportunistic pathogen associated with nosocomial bacterial …