The current nanomedicines for cancer therapy based on the enhance permeability and
retention (EPR) effect remain insufficient to satisfy the clinical need, and the challenges …

Although nanoparticles are expected to revolutionize cancer treatment, their low efficacy
remains the greatest limiting factor. Recent investigations found that nanoparticles' golden …

A desirable cancer therapeutic strategy is supposed to have effective ability to not only exert
maximum anticancer ability but also inspire antitumor immunity for preventing tumor relapse …

Nanomedicine-based phototherapy in combination with immune checkpoint blockade
therapy has been reported as a promising strategy for improved cancer immunotherapy …

Herein, we designed a dual-response shape transformation and charge reversal strategy
with chemo-photodynamic therapy to improve the blood circulation time, tumor penetration …

Background Hepatocellular carcinoma (HCC) is a common malignant tumor with high rate of
metastasis and recurrence. Although immune checkpoint blockade (ICB) has emerged as a …

Patients with primary and bone metastatic breast cancer have significantly reduced survival
and life quality. Due to the poor drug delivery efficiency of anti-metastasis therapy and the …

Abnormal metabolism of cancer cells results in complex tumor microenvironments (TME),
which play a dominant role in tumor metastasis. Herein, self-delivery ternary bioregulators …

Modulating tumor microenvironment to amplify the therapeutic efficiency would be a novel
strategy for effective cancer treatment. In this work, based on the TPZ-loaded porphyrinic …

Photodynamic therapy (PDT) can generate reactive oxygen species (ROS) to cause cell
apoptosis and induce immunogenic cell death (ICD) to activate immune response …