[HTML][HTML] Identification of mouse soleus muscle proteins altered in response to changes in gravity loading

Y Ino, T Ohira, K Kumagai, Y Nakai, T Akiyama… - Scientific Reports, 2023 - nature.com
Gravity-dependent physical processes strongly affect the ability of elderly people to maintain
musculoskeletal health by reducing muscle atrophy and increasing bone mineral density …

Proteome-wide adaptations of mouse skeletal muscles during a full month in space

G Tascher, T Brioche, P Maes, A Chopard… - Journal of proteome …, 2017 - ACS Publications
The safety of space flight is challenged by a severe loss of skeletal muscle mass, strength,
and endurance that may compromise the health and performance of astronauts. The …

Comparative proteomic analysis of the aging soleus and extensor digitorum longus rat muscles using TMT labeling and mass spectrometry

DFS Chaves, PC Carvalho, DB Lima… - Journal of proteome …, 2013 - ACS Publications
Sarcopenia describes an age-related decline in skeletal muscle mass, strength, and function
that ultimately impairs metabolism and leads to poor balance, frequent falling, limited …

[HTML][HTML] Gene Expression Profiling in Slow-Type Calf Soleus Muscle of 30 Days Space-Flown Mice

G Gambara, M Salanova, S Ciciliot, S Furlan… - PloS one, 2017 - journals.plos.org
Microgravity exposure as well as chronic disuse are two main causes of skeletal muscle
atrophy in animals and humans. The antigravity calf soleus is a reference postural muscle to …

Signatures of muscle disuse in spaceflight and bed rest revealed by single muscle fiber proteomics

M Murgia, S Ciciliot, N Nagaraj, C Reggiani… - PNAS …, 2022 - academic.oup.com
Astronauts experience dramatic loss of muscle mass, decreased strength, and insulin
resistance, despite performing daily intense physical exercise that would lead to muscle …

[HTML][HTML] Characterization of the skeletal muscle proteome in undernourished old rats

C Barbé, J Salles, C Chambon, C Giraudet… - International Journal of …, 2022 - mdpi.com
Aging is associated with a progressive loss of skeletal muscle mass and function termed
sarcopenia. Various metabolic alterations that occur with aging also increase the risk of …

Matrisome, innervation and oxidative metabolism affected in older compared with younger males with similar physical activity

B Lagerwaard, AG Nieuwenhuizen… - Journal of cachexia …, 2021 - Wiley Online Library
Background Due to the interaction between skeletal muscle ageing and lifestyle factors, it is
often challenging to attribute the decline in muscle mass and quality to either changes in …

[HTML][HTML] Identification of gravity-responsive proteins in the femur of spaceflight mice using a quantitative proteomic approach

K Egashira, Y Ino, Y Nakai, T Ohira, T Akiyama… - Journal of …, 2023 - Elsevier
Although the microgravity (μ-g) environment that astronauts encounter during spaceflight
can cause severe acute bone loss, the molecular mechanism of this bone loss remains …

Proteomic analysis of rat soleus muscle undergoing hindlimb suspension‐induced atrophy and reweighting hypertrophy

RJ Isfort, F Wang, KD Greis, Y Sun, TW Keough… - …, 2002 - Wiley Online Library
A proteomic analysis was performed comparing normal rat soleus muscle to soleus muscle
that had undergone either 0.5, 1, 2, 4, 7, 10 and 14 days of hindlimb suspension‐induced …

[HTML][HTML] Label-free quantitative protein profiling of vastus lateralis muscle during human aging

L Theron, M Gueugneau, C Coudy, D Viala… - Molecular & Cellular …, 2014 - ASBMB
Sarcopenia corresponds to the loss of muscle mass occurring during aging, and is
associated with a loss of muscle functionality. Proteomic links the muscle functional changes …