[HTML][HTML] Comparison of various chromatographic systems for analysis of cytisine in human serum, saliva and pharmaceutical formulation by HPLC with diode array …

K Wróblewski, A Petruczynik, T Tuzimski, D Przygodzka… - Molecules, 2019 - mdpi.com
Background: Identification and quantitative determination of cytisine, especially in biological
samples and pharmaceutical formulations, is still a difficult analytical task. Cytisine is an …

[HTML][HTML] Development and validation of LC-MS/MS method for determination of cytisine in human serum and saliva

K Wróblewski, M Szultka-Młyńska, RJ Courtney… - International Journal of …, 2023 - mdpi.com
Cytisine (CYT) is a quinolizidine alkaloid used for nicotine addiction treatment. Recent
clinical trial data regarding cytisine confirm its high effectiveness and safety as a smoking …

[PDF][PDF] Pharmacokinetics of cytisine after single intravenous and oral administration in rabbits

H Astroug, R Simeonova, L Kassabova… - Interdisciplinary …, 2010 - sciendo.com
The aim of this study is to develop a sensitive HPLC method for the quantitative
determination of cytisine in serum and to characterize the pharmacokinetic behaviour of …

[HTML][HTML] Determination of Cytisine and N-Methylcytisine from Selected Plant Extracts by High-Performance Liquid Chromatography and Comparison of Their Cytotoxic …

A Petruczynik, K Wróblewski, J Misiurek, T Plech… - Toxins, 2020 - mdpi.com
Quinolizidine alkaloids exhibit various forms of biological activity. A lot of them were found in
the Leguminosae family, including Laburnum and Genista. The aim of the study was the …

[HTML][HTML] Cytisine and cytisine derivatives. More than smoking cessation aids

C Gotti, F Clementi - Pharmacological research, 2021 - Elsevier
Cytisine, a natural bioactive compound that is mainly isolated from plants of the
Leguminosae family (especially the seeds of Laburnum anagyroides), has been marketed in …

[PDF][PDF] Development and validation of a RP-HPLC method for determination of citicoline monosodium in human plasma

SK Bindaiya, K Sahu, M Bhaisare… - Latin Am. J …, 2011 - researchgate.net
A sensitive and specific high performance reversed phase liquid chromatographic method
was developed for quantification of citicoline monosodium (CTM) in human plasma. The …

Plasma concentrations of cytisine, a commercially available plant-based alkaloid, in healthy adult smokers taking recommended doses for smoking cessation

SH Jeong, J Sheridan, D Newcombe, M Tingle - Xenobiotica, 2018 - Taylor & Francis
Cytisine is a plant alkaloid that is a partial agonist for the α4β2-nAChRs and is used as an
aid to smoking cessation. To date, there are no published data on cytisine concentrations in …

Analysis of terpene compounds in Cimicifuga foetida L. by reversed-phase high-performance liquid chromatography with evaporative light scattering detection

L Kong, X Li, H Zou, H Wang, X Mao, Q Zhang… - … of Chromatography A, 2001 - Elsevier
An RP-HPLC method with evaporative light scattering detection (ELSD) was developed for
the analysis of terpene compounds in traditional Chinese medicine. Actein, 27-deoxyactein …

Quantitative HPLC determination of cynaropicrin in Centaurea scabiosa dry extract

IP Kaminskii, EA Krasnov, TV Kadyrova… - Pharmaceutical …, 2011 - Springer
An HPLC method for quantitative determination of cynaropicrin in Centaurea scabiosa L. dry
extract obtained using 40% aqueous ethanol has been developed and its performance has …

The chemistry of van de Moer test for cytisine

F Sánchez-Viesca, R Gómez - Earthline Journal of …, 2021 - earthlinepublishers.com
Cytisine is an alkaloid with biological activity that is used as medication for smoking
cessation treatment. It is a quinolizidine derivative, one ring being 2-pyridinone, and there is …