Hydrogen sulfide inhibits high-salt diet-induced myocardial oxidative stress and myocardial hypertrophy in Dahl rats

P Huang, Z Shen, W Yu, Y Huang, C Tang… - Frontiers in …, 2017 - frontiersin.org
The study aimed to examine the protective effect of hydrogen sulfide (H2S) on high-salt-
induced oxidative stress and myocardial hypertrophy in salt-sensitive (Dahl) rats. Thirty male …

Dose-Dependent Effects of Long-Term Administration of Hydrogen Sulfide on Myocardial Ischemia–Reperfusion Injury in Male Wistar Rats: Modulation of RKIP, NF-κB …

S Jeddi, S Gheibi, K Kashfi, M Carlström… - International journal of …, 2020 - mdpi.com
Decreased circulating levels of hydrogen sulfide (H2S) are associated with higher mortality
following myocardial ischemia. This study aimed at determining the long-term dose …

Sodium hydrosulfide prevents myocardial dysfunction through modulation of extracellular matrix accumulation and vascular density

LL Pan, XL Wang, XL Wang, YZ Zhu - International Journal of Molecular …, 2014 - mdpi.com
The aim was to examine the role of exogenous hydrogen sulfide (H2S) on cardiac
remodeling in post-myocardial infarction (MI) rats. MI was induced in rats by ligation of …

[HTML][HTML] Protective effect of hydrogen sulphide against myocardial hypertrophy in mice

M Shao, C Zhuo, R Jiang, G Chen, J Shan, J Ping… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Cardiac hypertrophy is a critical component of phenotype in the failing heart. Recently,
increasing evidence has demonstrated that oxidative stress plays an important role in the …

Hydrogen Sulfide Improves Myocardial Remodeling via Downregulated Angiotensin Ⅱ/AT1R Pathway in Renovascular Hypertensive Rats

SY Liu, XC Duan, S Jin, X Teng, L Xiao… - American Journal of …, 2017 - academic.oup.com
Abstract BACKGROUND Hydrogen sulfide (H2S) is an important endogenous gaseous
transmitter in many physiological functions. Plasma H2S decreased, and angiotensin II (Ang …

Hydrogen sulfide attenuates the development of diabetic cardiomyopathy

X Zhou, G An, X Lu - Clinical Science, 2015 - portlandpress.com
There is growing evidence that H2S has beneficial effects in treatment of various
cardiovascular diseases. However, it remains unclear whether H2S can attenuate the …

Up Regulation of cystathione γ lyase and Hydrogen Sulphide in the Myocardium Inhibits the Progression of Isoproterenol–Caffeine Induced Left Ventricular …

A Ahmad, MA Sattar, HA Rathore, MH Abdulla… - PloS one, 2016 - journals.plos.org
Hydrogen sulphide (H2S) is an emerging molecule in many cardiovascular complications
but its role in left ventricular hypertrophy (LVH) is unknown. The present study explored the …

Nitric oxide synthase inhibition abrogates hydrogen sulfide-induced cardioprotection in mice

B Sojitra, Y Bulani, UK Putcha, A Kanwal… - Molecular and cellular …, 2012 - Springer
The cardioprotective property of hydrogen sulfide (H 2 S) is recently reported. However,
cellular signaling cascades mediated by H 2 S are largely unclear. This study was …

Antioxidant effects of hydrogen sulfide on left ventricular remodeling in smoking rats are mediated via PI3K/Akt-dependent activation of Nrf2

X Zhou, L Zhao, J Mao, J Huang… - Toxicological Sciences, 2015 - academic.oup.com
There is growing evidence that oxidative stress plays critical roles in the pathogenesis of
cardiac remodeling. In the present study, we established a rat model of passive smoking and …

Possible cardioprotective role of NaHS on ECG and oxidative stress markers in an unpredictable chronic mild stress model in rats

M Ghalwash, A Elmasry… - Canadian Journal of …, 2021 - cdnsciencepub.com
The protective effect of H2S against various body organ injuries has been described. The
aim of this work is to investigate the potential role of sodium hydrosulfide (NaHS) as an H2S …