Although survival of individuals with cystic fibrosis (CF) has been continuously improving for
the past 40 years, respiratory failure secondary to recurrent pulmonary infections remains …

Progressive obstructive lung disease secondary to chronic airway infection, coupled with
impaired host immunity, is the leading cause of morbidity and mortality in cystic fibrosis (CF) …

The chronic colonization of the lower airways by bacterial pathogens is the leading cause of
morbidity and mortality in patients with cystic fibrosis (CF). Pseudomonas aeruginosa is the …

This comprehensive State of the Art review summarizes the current published knowledge
base regarding the pathophysiology and microbiology of pulmonary disease in cystic …

Chronic suppurative lower airway infection is a hallmark feature of cystic fibrosis (CF).
Decades of experience in clinical microbiology have enabled the development of improved …

Cystic fibrosis (CF) is the most common lethal genetic disease in the Caucasian population,
and should be considered an infectious disease because of the basic pathophysiology …

Historically, H. influenzae and S. aureus were considered to be the primary organisms
infecting the airways of infants and children with CF, followed by P. aeruginosa or …

In patients afflicted with cystic fibrosis (CF), morbidity and mortality are primarily associated
with the adverse consequences of chronic microbial bronchial infections, which are thought …

Much of the improvement in the survival of individuals with cystic fibrosis (CF) is due to
advancements in antimicrobial treatments. New aerosolized antibiotic formulations have …

Cystic fibrosis (CF) is one of the most common life-shortening genetic diseases in
Caucasians. Due to abnormal accumulation of mucus, respiratory failure caused by chronic …