Background Prenatal exposure to ethanol (E t OH) reduces the expression of hypothalamic
proopiomelanocortin (POMC) gene, known to control various physiological functions …

Proopiomelanocortin (POMC) is a precursor gene of the neuropeptide β-endorphin in the
hypothalamus and is known to regulate various physiological functions including stress …

BACKGROUND: Neurons containing proopiomelanocortin (POMC)-derived peptides, known
to control stress axis, metabolic, and immune functions, have a lower function in patients …

Prenatal ethanol (EtOH) exposure is associated with low birth weight, followed by increased
appetite, catch-up growth, insulin resistance, and impaired glucose tolerance in the rat …

Background We have recently shown that binge or heavy levels of alcohol drinking increase
deoxyribonucleic acid (DNA) methylation and reduce gene expression of …

Prenatal exposure to ethanol (E) enhances the offspring's ACTH and corticosterone
responses to stressors. Here, we determined the role of increased pituitary responsiveness …

Background: Rats prenatally exposed to ethanol (E) exhibit hypothalamic–pituitary–adrenal
(HPA) hyperresponsiveness and changes in central HPA regulation following exposure to …

Prenatal alcohol exposure (PAE) programs the fetal hypothalamic-pituitary-adrenal (HPA)
axis, resulting in HPA dysregulation and hyperresponsiveness to stressors in adulthood …

The effect of preconception drinking by the mother on the life-long health outcomes of her
children is not known, and therefore, in this study using an animal model, we determined the …

Children and adults with fetal alcohol spectrum disorder (FASD) have elevated rates of
depression and anxiety disorders compared to control populations. The effects of prenatal …