Environmental insults and compensative responses: when microbiome meets cancer

S Nagpal, SS Mande - Discover Oncology, 2023 - Springer
Tumor microenvironment has recently been ascribed a new hallmark—the polymorphic
microbiome. Accumulating evidence regarding the tissue specific territories of tumor …

Microbiota in cancer: molecular mechanisms and therapeutic interventions

Z Chen, D Guan, Z Wang, X Li, S Dong, J Huang… - MedComm, 2023 - Wiley Online Library
The diverse bacterial populations within the symbiotic microbiota play a pivotal role in both
health and disease. Microbiota modulates critical aspects of tumor biology including cell …

Microbiome and the Hallmarks of Cancer

RM Bleich, JC Arthur - Inflammation, Infection, and Microbiome in Cancers, 2021 - Springer
Microbes have long been linked to cancer: from studies on Epstein–Barr virus (EBV) and
lymphoma to Helicobacter pylori and gastric cancer. Although single infectious agents were …

Future Perspectives: Microbiome, Cancer and Therapeutic Promise

S Banerjee, ES Robertson - Microbiome and Cancer, 2019 - Springer
A homeostatic balance exists between a host and its commensal microbes. Disturbance of
this homeostasis, a finely tuned system can result in diseases including cancer. Investigating …

[HTML][HTML] Functional role of the cancer microbiome in the solid tumour niche

EA Marshall, N Telkar, WL Lam - Current Research in Immunology, 2021 - Elsevier
The importance of gut microbiome to cancer therapy and response cannot be overstated,
however the contribution of the bacterial population to the local solid tumour ecosystem is …

The microbiome modulates the tumor macroenvironment

SE Erdman, T Poutahidis - Oncoimmunology, 2014 - Taylor & Francis
Earlier investigations of the tumor microenvironment unveiled systemic networks presenting
novel therapeutic opportunities. It has been recently shown that gut microbes modulate …

The cancer microbiome: distinguishing direct and indirect effects requires a systemic view

JB Xavier, VB Young, J Skufca, F Ginty, T Testerman… - Trends in cancer, 2020 - cell.com
The collection of microbes that live in and on the human body–the human microbiome–can
impact on cancer initiation, progression, and response to therapy, including cancer …

Could the tumor-associated microbiota be the new multi-faceted player in the tumor microenvironment?

AG Goubet - Frontiers in Oncology, 2023 - frontiersin.org
Microorganisms have been identified in tumor specimens for over a century. It is only in
recent years that tumor-associated microbiota has become a rapidly expanding field …

[HTML][HTML] Intratumoral Microbiome: Foe or Friend in Reshaping the Tumor Microenvironment Landscape?

AA Kyriazi, M Karaglani, S Agelaki, S Baritaki - Cells, 2024 - mdpi.com
The role of the microbiome in cancer and its crosstalk with the tumor microenvironment
(TME) has been extensively studied and characterized. An emerging field in the cancer …

Relevance of tumor microbiome in cancer incidence, prognosis, and its clinical implications in therapeutics

A Bahuguna, SK Dubey - Biochimica et Biophysica Acta (BBA)-Reviews on …, 2023 - Elsevier
The microbiota is garnering progressively greater consideration as an essential facet of the
tumor microenvironment that regulates tumor proliferation and affects cancer prognosis …