Client-centered adherence counseling with adherence measurement feedback to support use of the dapivirine ring in MTN-025 (The HOPE Study)
Fostering adherence and open communication about adherence challenges is key to
harnessing the potential of biomedical HIV prevention products. We describe the counseling …
harnessing the potential of biomedical HIV prevention products. We describe the counseling …
Women's experience receiving drug feedback and adherence counseling in MTN-025/HOPE-an HIV Prevention open-label trial of the Dapivirine Vaginal Ring
Abstract In the Phase IIIB MTN-025/HOPE open label extension trial, participants were
offered the dapivirine vaginal ring as HIV prophylaxis, and those who accepted the ring …
offered the dapivirine vaginal ring as HIV prophylaxis, and those who accepted the ring …
[HTML][HTML] Impact and experience of participant engagement activities in supporting dapivirine ring use among participants enrolled in the phase III MTN-020/ASPIRE …
M Garcia, E Luecke, AJ Mayo, R Scheckter, P Ndase… - BMC Public Health, 2021 - Springer
Background Low adherence to investigational products can negatively impact study
outcomes, limiting the ability to demonstrate efficacy. To continue advancing potential new …
outcomes, limiting the ability to demonstrate efficacy. To continue advancing potential new …
Patterns of adherence to a dapivirine vaginal ring for HIV-1 prevention among South African women in a phase iii randomized controlled trial
Background: Persistent use of HIV prevention methods can be a challenge, particularly for
some younger women. The long-acting, discreet, woman-centric dapivirine vaginal ring …
some younger women. The long-acting, discreet, woman-centric dapivirine vaginal ring …
Integration of a relationship-focused counseling intervention with delivery of the dapivirine ring for HIV prevention to women in Johannesburg: results of the …
ET Montgomery, ST Roberts, K Reddy, E Tolley… - AIDS and Behavior, 2021 - Springer
Biomedical, female-initiated HIV prevention methods can help reduce disproportionately
high HIV rates among women in sub-Saharan Africa, but male partner resistance and …
high HIV rates among women in sub-Saharan Africa, but male partner resistance and …
The power of the shared experience: MTN-020/ASPIRE trial participants' descriptions of peer influence on acceptability of and adherence to the dapivirine vaginal ring …
Women are disproportionately at risk of acquiring HIV in East and Southern Africa, despite
global declines in incidence. Female-initiated HIV prevention methods, like the dapivirine …
global declines in incidence. Female-initiated HIV prevention methods, like the dapivirine …
Implementation of a novel adherence monitoring strategy in a phase III, blinded, placebo-controlled, HIV-1 prevention clinical trial
MJ Husnik, ER Brown, M Marzinke… - JAIDS Journal of …, 2017 - journals.lww.com
Background: Placebo-controlled HIV-1 prevention trials of pre-exposure prophylaxis (PrEP)
have not generally used concurrent measurement of adherence because of the potential risk …
have not generally used concurrent measurement of adherence because of the potential risk …
Qualitative perceptions of dapivirine VR adherence and drug level feedback following an open-label extension trial
K Naidoo, LE Mansoor, AWK Katz… - JAIDS Journal of …, 2021 - journals.lww.com
Background: There continues to be a need for HIV prevention options that women can
initiate and use autonomously. The dapivirine vaginal ring (VR) has been shown to have a …
initiate and use autonomously. The dapivirine vaginal ring (VR) has been shown to have a …
Implementation of a fidelity monitoring process to assess delivery of an evidence-based adherence counseling intervention in a multi-site biomedical HIV prevention …
ABSTRACT Pre-Exposure Prophylaxis (PrEP) trials often implement counseling to support
product adherence. Counseling fidelity can vary significantly across providers and time …
product adherence. Counseling fidelity can vary significantly across providers and time …
[PDF][PDF] A qualitative evaluation of women's experience receiving drug feedback in MTN-025/HOPE-an HIV prevention open-label trial of the dapivirine vaginal ring
Background• Ring residual drug levels (RDL) in returned rings are used as a biomarker of
ring adherence. 1, 8• RDL scores are calculated by dividing amount of residual DPV in ring …
ring adherence. 1, 8• RDL scores are calculated by dividing amount of residual DPV in ring …