There is extensive experimental evidence that oxidative damage permanently occurs to
lipids of cellular membranes, proteins, and DNA. In nuclear and mitochondrial DNA, 8 …

Reactive oxygen species (ROS) produced either endogenously or exogenously can attack
lipid, protein and nucleic acid simultaneously in the living cells. In nuclear and mitochondrial …

Oxidative DNA damage is considered to play an important role in pathophysiological
processes, ageing and cancer. So far major interest has been on measuring 8-hydroxy-2 …

Living organisms are continuously exposed to reactive oxygen species as a consequence of
biochemical reactions as well as external factors. Oxidative DNA damage has been …

Hydroxydeoxyguanosine (8-OHdG) is a widely-used biomarker of oxidative DNA damages.
8-OHdG in peripheral blood leukocyte is associated with mutation and cancer risk. The level …

8-hydroxy-2′-deoxyguanosine (8-OH-dG) was first reported in 1984 as a major form of
oxidative DNA damage product by heated sugar, Fenton-type reagents and X-irradiation in …

We are attempting to resolve some of the problems encountered in measuring 8-hydroxy-
2′-deoxyguanosine (8-oxodG) in human cellular DNA as a marker of oxidative stress …

HPLC with electrochemical detection (HPLC-EC) is a highly sensitive and a selective
method for detecting 8-hydroxy-2′-deoxyguanosine (oh 8 dG), a biomaker of oxidative …

Oxidative DNA damage plays crucial roles in the pathogenesis of numerous diseases
including cancer. 8-hydroxy-2′-deoxyguanosine (8-OHdG) is the most representative …

8-Hydroxydeoxyguanosine (8-OHdG) has been widely used as a biomarker of oxidative
DNA damage in both animal and human studies. However, controversial data exist on the …