Metabolic signature of energy metabolism alterations and excess nitric oxide production in culture media correlate with low human embryo quality and unsuccessful …
R Pallisco, G Lazzarino, G Bilotta, F Marroni… - International Journal of …, 2023 - mdpi.com
Notwithstanding the great improvement of ART, the overall rate of successful pregnancies
from implanted human embryos is definitely low. The current routine embryo quality …
from implanted human embryos is definitely low. The current routine embryo quality …
Non-invasive human embryo metabolic assessment as a developmental criterion
M Motiei, K Vaculikova, A Cela, K Tvrdonova… - Journal of Clinical …, 2020 - mdpi.com
The selection of a highly-viable single embryo in assisted reproductive technology requires
an acceptable predictive method in order to reduce the multiple pregnancy rate and …
an acceptable predictive method in order to reduce the multiple pregnancy rate and …
Applying metabolomic analyses to the practice of embryology: physiology, development and assisted reproductive technology
RL Krisher, AL Heuberger, M Paczkowski… - Reproduction …, 2015 - CSIRO Publishing
The advent of metabolomics technology and its application to small samples has allowed us
to non-invasively monitor the metabolic activity of embryos in a complex culture …
to non-invasively monitor the metabolic activity of embryos in a complex culture …
GC-MS/MS analysis of metabolites derived from a single human blastocyst
N Inoue, Y Nishida, E Harada, K Sakai, H Narahara - Metabolomics, 2021 - Springer
Introduction The field of assisted reproductive technology (ART) has significantly advanced;
however, morphological evaluation remains as the chosen method of assessment of embryo …
however, morphological evaluation remains as the chosen method of assessment of embryo …
Solution NMR in human embryo culture media as an option for assessment of embryo implantation potential
AM Salmerón, AC Abreu, M Vilches‐Ferrón… - NMR in …, 2021 - Wiley Online Library
NMR offers the potential to holistically screen hundreds of metabolites and has already
proved to be a powerful technique able to provide a global picture of metabolic changes in a …
proved to be a powerful technique able to provide a global picture of metabolic changes in a …
Metabolomics and its application for non-invasive embryo assessment in IVF
Morphology and cleavage rate remain the mainstay of embryo assessment. However, a
number of additional technologies for this application are under investigation. These include …
number of additional technologies for this application are under investigation. These include …
Metabolomics Integration in Assisted Reproductive Technologies for Enhanced Embryo Selection beyond Morphokinetic Analysis
S Pinto, B Guerra-Carvalho, L Crisóstomo… - International Journal of …, 2023 - mdpi.com
Embryo quality evaluation during in vitro development is a crucial factor for the success of
assisted reproductive technologies (ARTs). However, the subjectivity inherent in the …
assisted reproductive technologies (ARTs). However, the subjectivity inherent in the …
[HTML][HTML] Noninvasive metabolomic profiling as an adjunct to morphology for noninvasive embryo assessment in women undergoing single embryo transfer
E Seli, CG Vergouw, H Morita, L Botros, P Roos… - Fertility and sterility, 2010 - Elsevier
OBJECTIVE: To determine whether metabolomic profiling of spent embryo culture media
correlates with reproductive potential of human embryos. DESIGN: Retrospective study …
correlates with reproductive potential of human embryos. DESIGN: Retrospective study …
NMR studies of preimplantation embryo metabolism in human assisted reproductive techniques: a new biomarker for assessment of embryo implantation potential
There has been growing interest in understanding energy metabolism in human embryos
generated using assisted reproductive techniques (ART) for improving the overall success …
generated using assisted reproductive techniques (ART) for improving the overall success …
[HTML][HTML] Analysis of metabolism to select viable human embryos for transfer
DK Gardner, PL Wale - Fertility and sterility, 2013 - Elsevier
As we move to reducing the number of embryos transferred in a given IVF cycle, ideally
down to one, there is an ever-increasing need for noninvasive quantitative markers of …
down to one, there is an ever-increasing need for noninvasive quantitative markers of …
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