Age-related central gain compensation for reduced auditory nerve output for people with normal audiograms, with and without tinnitus

PT Johannesen, EA Lopez-Poveda - Iscience, 2021 - cell.com
Central gain compensation for reduced auditory nerve output has been hypothesized as a
mechanism for tinnitus with a normal audiogram. Here, we investigate if gain compensation …

Pump up the volume: could excessive neural gain explain tinnitus and hyperacusis?

H Brotherton, CJ Plack, M Maslin, R Schaette… - Audiology and …, 2015 - karger.com
Naturally occurring stimuli can vary over several orders of magnitude and may exceed the
dynamic range of sensory neurons. As a result, sensory systems adapt their sensitivity by …

Comparisons of auditory brainstem response and sound level tolerance in tinnitus ears and non-tinnitus ears in unilateral tinnitus patients with normal audiograms

HJ Shim, YH An, DH Kim, JE Yoon, JH Yoon - PloS one, 2017 - journals.plos.org
Objective Recently,“hidden hearing loss” with cochlear synaptopathy has been suggested
as a potential pathophysiology of tinnitus in individuals with a normal hearing threshold …

[HTML][HTML] Neurophysiological correlates of residual inhibition in tinnitus: Hints for trait-like EEG power spectra

S Schoisswohl, M Schecklmann, B Langguth… - Clinical …, 2021 - Elsevier
Objective To investigate oscillatory brain activity changes following acoustic stimulation in
tinnitus and whether these changes are associated with behavioral measures of tinnitus …

The effect of auditory residual inhibition on tinnitus and the electroencephalogram

ROC King, GS Shekhawat, C King, E Chan… - Ear and …, 2021 - journals.lww.com
Objectives: Tinnitus is the perception of sound in the absence of an external physical sound
source, for some people it can severely reduce the quality of life. Acoustic residual inhibition …

The auditory sensitivity is increased in tinnitus ears

S Hébert, P Fournier, A Noreña - Journal of Neuroscience, 2013 - Soc Neuroscience
Increased auditory sensitivity, also called hyperacusis, is a pervasive complaint of people
with tinnitus. The high prevalence of hyperacusis in tinnitus subjects suggests that both …

Tinnitus with a normal audiogram: physiological evidence for hidden hearing loss and computational model

R Schaette, D McAlpine - Journal of Neuroscience, 2011 - Soc Neuroscience
Ever since Pliny the Elder coined the term tinnitus, the perception of sound in the absence of
an external sound source has remained enigmatic. Traditional theories assume that tinnitus …

Evoked potentials reveal noise exposure–related central auditory changes despite normal audiograms

NF Bramhall, CE Niemczak, SD Kampel… - American journal of …, 2020 - ASHA
Purpose Complaints of auditory perceptual deficits, such as tinnitus and difficulty
understanding speech in background noise, among individuals with clinically normal …

[HTML][HTML] Increased intensity discrimination thresholds in tinnitus subjects with a normal audiogram

B Epp, J Hots, JL Verhey, R Schaette - The Journal of the Acoustical …, 2012 - pubs.aip.org
Recent auditory brain stem response measurements in tinnitus subjects with normal
audiograms indicate the presence of hidden hearing loss that manifests as reduced neural …

Auditory brainstem response demonstrates that reduced peripheral auditory input is associated with self-report of tinnitus

NF Bramhall, GP McMillan, FJ Gallun… - The Journal of the …, 2019 - pubs.aip.org
Tinnitus is one of the predicted perceptual consequences of cochlear synaptopathy, a type
of age-, noise-, or drug-induced auditory damage that has been demonstrated in animal …