All aspects of cellular RNA metabolism and processing involve DExH/D proteins, which are
a family of enzymes that unwind or manipulate RNA in an ATP-dependent fashion. DExH/D …

All aspects of cellular RNA metabolism and the replication of many viruses require DExH/D
proteins that manipulate RNA in a manner that requires nucleoside triphosphates. Although …

Members of the DExH/D superfamily of nucleic acid–activated nucleotide triphosphatases
are essential for virtually all aspects of RNA metabolism, including pre–messenger RNA …

The DExH/D protein family is the largest group of enzymes in eukaryotic RNA metabolism.
DExH/D proteins are mainly known for their ability to unwind RNA duplexes in an ATP …

DExH/D box proteins are required for the major transactions of RNA, including mRNA
synthesis, pre-mRNA splicing, ribosome biogenesis, translation and RNA decay. In the …

DExH/D proteins catalyze NTP-driven rearrangements of RNA and RNA-protein complexes
during most aspects of RNA metabolism. Although the vast majority of DExH/D proteins …

In eukaryotic cells, all aspects of cellular RNA metabolism require putative RNA helicases of
the DEAD and DExH protein families (collectively known as DExD/H families). Based on …

DExD/H-box proteins are ubiquitously involved in RNA-mediated processes and use ATP to
accelerate conformational changes in RNA. However, their mechanisms of action, and what …

Helicases unwind RNA or DNA duplexes and displace proteins from nucleic acids in an ATP-
dependent fashion. To unwind duplexes, helicases typically load onto one of the two nucleic …

DEXD/H-box RNA helicases couple ATP hydrolysis to RNA remodeling by an unknown
mechanism. We used x-ray crystallography and biochemical analysis of the human DEXD/H …