Myocardial infarction is the most common cause of cardiac injury and results in acute loss of
a large number of myocardial cells. Because the heart has negligible regenerative capacity …

Extensive necrosis of ischemic cardiomyocytes in the infarcted myocardium activates the
innate immune response triggering an intense inflammatory reaction. Release of danger …

The accumulation of immune cells is among the earliest responses that manifest in the
cardiac tissue after injury. Both innate and adaptive immunity coordinate distinct and …

The immune system plays a critical role in both repair and remodeling of the infarcted
myocardium. Danger signals released by dying cardiomyocytes mobilize, recruit, and …

Myocardial infarction (MI) is one of the major contributors to worldwide morbidity and
mortality. It is atherosclerosis' most dreadful complication and occurs after the supply of …

Following an insult by both intrinsic and extrinsic pathways, complex cellular, and molecular
interactions determine a successful recovery or inadequate repair of damaged tissue. The …

Introduction The immune system plays a crucial role in the initiation, development, and
resolution of inflammation following myocardial infarction (MI). The lack of oxygen and …

Despite the advances that have been made in developing new therapeutics, cardiovascular
disease remains the leading cause of worldwide mortality. Therefore, understanding the …

In adult mammals, massive sudden loss of cardiomyocytes after infarction overwhelms the
limited regenerative capacity of the myocardium, resulting in the formation of a collagen …

The burden of heart failure (HF), developing after myocardial infarction MI, still represents a
major issue in clinical practice. Failure of appropriate resolution of inflammation during post …