Age at menarche and osteoporosis: a Mendelian randomization study
Purpose Traditional epidemiological studies suggest that there is an association between
age at menarche (years)(AAM) and bone mineral density (BMD) at the sites of the femoral …
age at menarche (years)(AAM) and bone mineral density (BMD) at the sites of the femoral …
Genetic and environmental correlations between age at menarche and bone mineral density at different skeletal sites
Low bone mineral density (BMD) is an important risk factor for osteoporotic fractures.
Though previous studies have demonstrated that age at menarche (AAM) is phenotypically …
Though previous studies have demonstrated that age at menarche (AAM) is phenotypically …
Genetically determined later puberty impacts lowered bone mineral density in childhood and adulthood
Later puberty associates with lower areal bone mineral density (aBMD), and both are risk
factors for osteoporosis. However, the association between puberty timing–associated …
factors for osteoporosis. However, the association between puberty timing–associated …
Bivariate genome-wide association analyses identified genes with pleiotropic effects for femoral neck bone geometry and age at menarche
Femoral neck geometric parameters (FNGPs), which include cortical thickness (CT),
periosteal diameter (W), buckling ratio (BR), cross-sectional area (CSA), and section …
periosteal diameter (W), buckling ratio (BR), cross-sectional area (CSA), and section …
Identifying potential causal effects of age at menopause: a Mendelian randomization phenome-wide association study
Age at natural menopause (ANM) is associated with a range of health-related traits,
including bone health, female reproductive cancers, and cardiometabolic health. Our …
including bone health, female reproductive cancers, and cardiometabolic health. Our …
Causal relationships between sex hormone traits, lifestyle factors, and osteoporosis in men: A Mendelian randomization study
H Wang, J Cheng, D Wei, H Wu, J Zhao - Plos one, 2022 - journals.plos.org
Although observational studies have explored factors that may be associated with
osteoporosis, it is not clear whether they are causal. Osteoporosis in men is often …
osteoporosis, it is not clear whether they are causal. Osteoporosis in men is often …
Review of mendelian randomization studies on age at natural menopause
X Zhang, Z Huangfu, S Wang - Frontiers in Endocrinology, 2023 - frontiersin.org
Menopause marks the end of the reproductive phase of life. Based on epidemiological
studies, abnormal age at natural menopause (ANM) is thought to contribute to a number of …
studies, abnormal age at natural menopause (ANM) is thought to contribute to a number of …
Chromosomal regions 22q13 and 3p25 may harbor quantitative trait loci influencing both age at menarche and bone mineral density
Late age at menarche (AAM), an important type of endocrinopathy in females, is associated
with lower bone mineral density (BMD), a major risk factor for osteoporosis. The correlation …
with lower bone mineral density (BMD), a major risk factor for osteoporosis. The correlation …
Birth weight is positively associated with adult osteoporosis risk: observational and Mendelian randomization studies
The relationship between birth weight and osteoporosis was inconsistent in previous
observational studies. Therefore, we performed a systematic evaluation to determine the …
observational studies. Therefore, we performed a systematic evaluation to determine the …
Identifying potential causal effects of age at menarche: a Mendelian randomization phenome-wide association study
Background Age at menarche has been associated with various health outcomes. We aimed
to identify potential causal effects of age at menarche on health-related traits in a hypothesis …
to identify potential causal effects of age at menarche on health-related traits in a hypothesis …