Pathological differences between white and grey matter multiple sclerosis lesions
M Prins, E Schul, J Geurts… - Annals of the New …, 2015 - Wiley Online Library
Multiple sclerosis (MS) is a debilitating disease characterized by demyelination of the central
nervous system (CNS), resulting in widespread formation of white matter lesions (WMLs) …
nervous system (CNS), resulting in widespread formation of white matter lesions (WMLs) …
Relationship between white matter lesions and gray matter atrophy in multiple sclerosis: a systematic review
IA Lie, MM Weeda, RM Mattiesing, MAE Mol… - Neurology, 2022 - AAN Enterprises
Background and Objectives There is currently no consensus about the extent of gray matter
(GM) atrophy that can be attributed to secondary changes after white matter (WM) lesions or …
(GM) atrophy that can be attributed to secondary changes after white matter (WM) lesions or …
Grey matter pathology in clinically early multiple sclerosis: evidence from magnetic resonance imaging
D Chard, D Miller - Journal of the neurological sciences, 2009 - Elsevier
In multiple sclerosis (MS) it is emerging that the most visible element of pathology, white
matter (WM) lesions, represents only a fraction of the disease burden borne by the brain; …
matter (WM) lesions, represents only a fraction of the disease burden borne by the brain; …
Gray matter involvement in multiple sclerosis
I Pirko, CF Lucchinetti, S Sriram, R Bakshi - Neurology, 2007 - AAN Enterprises
Gray matter (GM) involvement is detected even in the earliest stages of multiple sclerosis
(MS), and GM atrophy occurs at a faster rate than white matter (WM) atrophy early in the …
(MS), and GM atrophy occurs at a faster rate than white matter (WM) atrophy early in the …
MRI evidence for multiple sclerosis as a diffuse disease of the central nervous system
The classical view of MS as a chronic inflammatory demyelinating disease leading to the
formation of focal central nervous system (CNS) white matter (WM) lesions has been …
formation of focal central nervous system (CNS) white matter (WM) lesions has been …
Exploring the origins of grey matter damage in multiple sclerosis
M Calabrese, R Magliozzi, O Ciccarelli… - Nature Reviews …, 2015 - nature.com
Multiple sclerosis is characterized at the gross pathological level by the presence of
widespread focal demyelinating lesions of the myelin-rich white matter. However, it is …
widespread focal demyelinating lesions of the myelin-rich white matter. However, it is …
Grey matter damage in multiple sclerosis: a pathology perspective
Over the past decade, immunohistochemical studies have provided compelling evidence
that gray matter (GM) pathology in multiple sclerosis (MS) is extensive. Until recently, this …
that gray matter (GM) pathology in multiple sclerosis (MS) is extensive. Until recently, this …
Gray and normal-appearing white matter in multiple sclerosis: an MRI perspective
H Vrenken, JJG Geurts - Expert review of neurotherapeutics, 2007 - Taylor & Francis
Besides focal white matter lesions, multiple sclerosis brain tissue also displays
abnormalities in the gray matter and the normal-appearing white matter. Recent advances in …
abnormalities in the gray matter and the normal-appearing white matter. Recent advances in …
[HTML][HTML] Advances in understanding gray matter pathology in multiple sclerosis: are we ready to redefine disease pathogenesis?
R Zivadinov, I Pirko - BMC neurology, 2012 - Springer
The purpose of this special issue in BMC Neurology is to summarize advances in our
understanding of the pathological, immunological, imaging and clinical concepts of gray …
understanding of the pathological, immunological, imaging and clinical concepts of gray …
Multiple sclerosis: a white matter disease with associated gray matter damage
M Filippi - Journal of the neurological sciences, 2001 - jns-journal.com
Ž. The traditional description of multiple sclerosis MS emphasizes the notion that this
disease is an inflammatoryrdemyelinating condition of the white matter of the Ž. central …
disease is an inflammatoryrdemyelinating condition of the white matter of the Ž. central …