The anterior pituitary is derived from Rathke's pouch arising from the oral ectoderm. The
initial apparently uniform precursor cells proliferate and differentiate into six different cell …

Many common morphogenic, signaling and transcriptional hierarchy themes exist with
respect to a number of different model systems representing mammalian organogenesis …

▪ Abstract During the development of the pituitary gland, distinct hormone-producing cell
types arise from a common population of ectodermal progenitors, providing an instructive …

Significant advances have been made in defining the transcription cascade that is
responsible for the early steps of pituitary formation and the environmental signals that …

During development of the mammalian pituitary gland, specific hormone-producing cell
types, critical in maintaining homeostasis, emerge in a spatially and temporally specific …

The pituitary gland has a relatively simple organization despite its central role as chef
d'orchestre of the endocrine system. Indeed, the glandular portion of the pituitary comprised …

The pituitary gland is a central endocrine organ regulating basic physiological functions,
including growth, the stress response, reproduction, metabolic homeostasis, and lactation …

The factors that play a role in pituitary development have been identified as transcription
factors and growth factors that regulate cell migration, proliferation and differentiation. These …

The mammalian anterior pituitary gland is a compound endocrine organ that regulates
reproductive development and fitness, growth, metabolic homeostasis, the response to …

The development of the pituitary gland has provided an instructive model system for
exploring the mechanisms by which differentiated cell types arise from a common …