Developmental studies in multicellular model organisms such as Caernohabditis elegans
rely extensively on the ability to cultivate and image animals repeatedly at the cell or …

Direct observation of developmental and physiological changes in certain model organisms
over time has been technically challenging. In the model organism Caenorhabditis elegans …

Studies of the real-time dynamics of embryonic development require a gentle embryo
handling method, the possibility of long-term live imaging during the complete …

Micro fabricated fluidic devices provide an accessible micro-environment for in vivo studies
on small organisms. Simple fabrication processes are available for microfluidic devices …

The nematode Caenorhabditis elegans is an important model organism in research on
neuroscience and development because of its stereotyped anatomy, relevance to human …

Long-term studies of Caenorhabditis elegans larval development traditionally require
tedious manual observations because larvae must move to develop, and existing …

Live-imaging of C. elegans is essential for the study of conserved cellular pathways (eg
EGFR/Wnt signaling) and morphogenesis in vivo. However, the usefulness of live imaging …

The nematode Caenorhabditis elegans is an important model organism for biomedical
research and genetic studies relevant to human biology and disease. Such studies are often …

This paper describes the fabrication of a microfluidic device for rapid immobilization of large
numbers of live C. elegans for performing morphological analysis, microsurgery, and …

Several microfluidic-based methods for Caenorhabditis elegans imaging have recently been
introduced. Existing methods either permit imaging across multiple larval stages without …