Reasons and evolution of non-thrombolysis in acute ischaemic stroke

T Reiff, P Michel - Emergency Medicine Journal, 2017 - emj.bmj.com
Introduction Despite increasing evidence of its efficacy in advanced age or in mild or severe
strokes, intravenous thrombolysis remains underused for acute ischaemic stroke (AIS). Our …

[HTML][HTML] Understanding the reasons behind the low utilisation of thrombolysis in stroke

A Eissa, I Krass, C Levi, J Sturm, R Ibrahim… - The Australasian …, 2013 - ncbi.nlm.nih.gov
Background Thrombolysis remains the only approved therapy for acute ischaemic stroke
(AIS); however, its utilisation is reported to be low. Aims This study aimed to determine the …

Thrombolysis enters the race: a new era for acute ischaemic stroke?

G Famularo, S Polchi, A Panegrossi - European Journal of …, 1998 - journals.lww.com
Thrombolysis has been shown to be an effective treatment for ischaemic stroke. The major
obstacles to more widespread use of this therapy are lack of awareness that treatment is …

Mild stroke and advanced age are the major reasons for exclusion from thrombolysis in stroke patients admitted within 4.5 hours

Y Liu, H Zhao, J Zhou, Q Wang, Z Chen… - Journal of Stroke and …, 2014 - Elsevier
Background Only 2%-3% of patients with acute ischemic stroke receive thrombolysis. The
aim of this study was to identify the reasons for exclusion from thrombolysis in patients …

Off-label thrombolysis for acute ischemic stroke: rate, clinical outcome and safety are influenced by the definition of 'minor stroke'

L Breuer, C Blinzler, HB Huttner, IC Kiphuth… - Cerebrovascular …, 2011 - karger.com
Background: Several contraindications for intravenous thrombolysis are not based on
controlled trials. Specialized stroke centers often apply less restrictive criteria. The aim of our …

Barriers to the utilization of thrombolysis for acute ischaemic stroke

A Eissa, I Krass, BV Bajorek - Journal of clinical pharmacy and …, 2012 - Wiley Online Library
What is known and Objective: Thrombolysis is currently the only evidence‐based
pharmacological treatment available for acute ischaemic stroke (AIS); however, its current …

Lack of experience of intravenous thrombolysis for acute ischaemic stroke does not influence the proportion of patients treated

A Kobayashi, M Skowronska, T Litwin… - Emergency medicine …, 2007 - emj.bmj.com
Objectives: To determine the eligibility of patients with ischaemic stroke admitted to the 2nd
Department of Neurology, Institute of Psychiatry and Neurology, Warsaw, Poland, for …

Why is there still a debate regarding the safety and efficacy of intravenous thrombolysis in the management of presumed acute ischaemic stroke? A systematic review …

L Donaldson, E Fitzgerald, O Flower… - Emergency Medicine …, 2016 - Wiley Online Library
Objective The objective of the present study is to independently and systematically assess
the harms and benefits of intravenous thrombolysis for patients with presumed acute …

A systematic review of barriers to delivery of thrombolysis for acute stroke

J Kwan, P Hand, P Sandercock - Age and ageing, 2004 - academic.oup.com
Background and purpose: barriers within the patient pathway can prevent early
administration of thrombolytic therapy in patients admitted with acute stroke. This systematic …

Off-label thrombolysis versus full adherence to the current European Alteplase license: impact on early clinical outcomes after acute ischemic stroke

M Cappellari, G Moretto, N Micheletti, F Donato… - Journal of thrombosis …, 2014 - Springer
Abstract According to current European Alteplase license, therapeutic-window for
intravenous (IV) thrombolysis in acute ischemic stroke has recently been extended to 4.5 h …