Enveloped viruses enter target cells by membrane fusion or endocytosis. In the latter case,
fusion of the viral envelope is induced by the acidic pH of the endocytic vesicle [1]. As with …

Cytoplasmic entry of HIV-1 requires binding of the viral glycoproteins to the cellular receptor
and coreceptor, leading to fusion of viral and cellular membranes. Early studies suggested …

Virions of the type 1 human immunodeficiency virus (HIV-1) can enter target cells by fusion
or endocytosis, with sharply different functional consequences. Fusion promotes productive …

The major pathway for HIV internalization in CD4+ T cells has been thought to be the direct
fusion of virus and cell membranes, because the cell surface is the point of entry of infectious …

HIV Entry Revisited: Cell Skip to Main Content Advertisement Cell This journal offers authors
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Highlights•I discuss controversial findings regarding the HIV entry sites into host cells.•There
is evidence both for HIV fusion with the plasma membrane and endosomes.•New evidence …

Enveloped animal viruses enter their host cells by a process of membrane fusion. This
fusion can occur at the cell plasma membrane or within the endocytic vacuolar system …

CD4 functions as the cell-surface receptor for human immunodeficiency virus (HIV);
however, the mechanism of virus entry into susceptible cells is unknown. To explore this …

HIV-1 envelope glycoprotein [Env; trimeric (gp160) 3 cleaved to (gp120/gp41) 3] attaches
the virion to a susceptible cell and induces fusion of viral and cell membranes to initiate …