Several methods have been developed for generating 3D, in vitro, organ-on-chip models of
human vasculature to study vascular function, transport, and tissue engineering. However …

Generating perfusable 3D microvessels in vitro is an important goal for tissue engineering,
as well as for reliable modelling of blood vessel function. To date, in vitro blood vessel …

To understand how the microvasculature grows and remodels, researchers require
reproducible systems that emulate the function of living tissue. Innovative contributions …

Vessel geometries in microengineered in vitro vascular models are important to recapitulate
a pathophysiological microenvironment for the study of flow-induced endothelial dysfunction …

Abstract Organ-on-a-chip (OOC) platforms involve the miniaturization of cell culture systems
and enable a variety of novel experimental approaches. These range from modeling the …

Organ-on-a-chip devices, also known as microphysiological systems, have gained
significant attention in recent years. Recent advances in tissue engineering and …

This paper reports a method for generating an intact and perfusable microvascular network
that connects to microfluidic channels without appreciable leakage. This platform …

Improving the biological relevance of organs-on-chips is one of the main issues in
biomedical engineering. The microvascular system is related to numerous biological …

Abstract Design and fabrication of effective biomimetic vasculatures constitutes a relevant
and yet unsolved challenge, lying at the heart of tissue repair and regeneration strategies …

Advances in tissue engineering, cell biology, microfabrication, and microfluidics have led to
the development of a wide range of vascular models. Here, we review platforms based on …