Osteoarthritis (OA), one of the most common rheumatic disorders, is characterized by
cartilage breakdown and by synovial inflammation that is directly linked to clinical symptoms …

Modern concepts of osteoarthritis (OA) have been forever changed by modern imaging
phenotypes demonstrating complex and multi-tissue pathologies involving cartilage …

Research into the pathophysiology of osteoarthritis (OA) has focused on cartilage and peri-
articular bone, but there is increasing recognition that OA affects all of the joint tissues …

Osteoarthritis (OA) is a progressive degenerative disease resulting in joint deterioration.
Synovial inflammation is present in the OA joint and has been associated with radiographic …

This review focuses on the recent advancements in the understanding of innate immunity in
the pathogenesis of osteoarthritis, particularly with attention to the roles of damage …

Osteoarthritis (OA) has traditionally been classified as a noninflammatory arthritis; however,
the dichotomy between inflammatory and degenerative arthritis is becoming less clear with …

Osteoarthritis (OA) is considered to be primarily a disease of the hyaline articular cartilage,
which secondarily affects subchondral bone and synovial membrane. The exact nature and …

Although cartilage degeneration characterizes human osteoarthritis (OA), changes also
involve the participation of the synovial membrane and the subchondral bone. In this review …

Osteoarthritis (OA) has long been considered a “wear and tear” disease leading to loss of
cartilage. OA used to be considered the sole consequence of any process leading to …

Osteoarthritis (OA) is often a progressive and disabling disease, which occurs in the setting
of a variety of risk factors–such as advancing age, obesity and trauma–that collude to incite …