As one of the most serious threats to human being, cancer is hard to be treated when
metastasis happens. What's worse, there are few identified targets of metastasis for drug …

Metastasis is directly or indirectly responsible for the majority of cancer deaths. Anti-
metastasis treatment is thus the key to cure cancer. Recent development in nanomedicine …

The complex tumor microenvironment is a most important factor in cancer development. The
biological microenvironment is composed of a variety of barriers including the extracellular …

Tumor immunotherapy is an artificial stimulation of the immune system to enhance anti-
cancer response. It has become a powerful clinical strategy for treating cancer. The number …

Tumor metastasis and recurrence is one of the biggest problems in curing cancers. Due to
the difficulty in complete removal of the primary tumor in traditional surgeries and the poor …

The tumor development and metastasis are closely related to the structure and function of
the tumor microenvironment (TME). Recently, TME modulation strategies have attracted …

Metastasis is the leading cause of cancer‐associated death, with poor prognosis even after
extensive treatment. The dormancy of metastatic cancer cells during dissemination or after …

One of the standards for cancer treatment is cancer immunotherapy which treats both
primary and metastasized tumors. Although cancer immunotherapeutics show better …

Cancer nanomedicines have shown promise in combination immunotherapy, thus far mostly
preclinically but also already in clinical trials. Combining nanomedicines with …

Tumor penetration is important for effectively tumor targeting drug delivery. Recently, many
researches are published to overcome the barriers that restrict tumor penetration and …