Epigenetic research has the potential to improve our understanding of the pathogenesis of
cancer, specifically non-small-cell lung cancer, and support our efforts to personalize the …

In 2015, lung cancer accounted for an estimated 221,200 new cancer diagnoses and
158,040 deaths in the United States, with the majority being attributable to cigarette …

Lung cancer remains the number one cause of cancer-related deaths worldwide with
221,200 estimated new cases and 158,040 estimated deaths in 2015. Approximately 80% of …

Lung cancer is the leading cause of cancer‐related mortality worldwide. Tumorigenesis
involves a multistep process resulting from the interactions of genetic, epigenetic, and …

Recent discoveries that non–small cell lung cancer (NSCLC) can be divided into molecular
subtypes based on the presence or absence of driver mutations have revolutionized the …

The epigenetic landscape, which in part includes DNA methylation, chromatin organization,
histone modifications, and noncoding RNA regulation, greatly contributes to the …

Lung cancer is the leading cause of cancer-related mortality worldwide. Advances in our
understanding of the genomics of lung cancer have led to substantial progress in the …

Non-small cell lung cancer (NSCLC) still constitutes the most common cancer-related cause
of death worldwide. All efforts to introduce suitable treatment options using …

Background Lung cancer remains the most common cause of cancer-related death, with a 5-
year survival rate of only 18%. In recent years, the development of targeted pharmacological …

Lung cancer is still the major cause of cancer-related mortality around the globe. The
interplay of permanent genetic and dynamic epigenetic changes leads to the onset and …