The co-amorphous (CAM) system has attracted widely attention for improving the solubility
of poor water solubility drug and provide a formulation strategy for combination …

The aim of the present investigation was to evaluate the effect of supersaturation on the oral
absorption of paclitaxel (PTX) in vivo. To achieve this, a PTX amorphous solid dispersion …

Paclitaxel (PTX) is efficacious in treating various solid tumors. However, the severe adverse
effects of its present formulation (Cremophor EL and ethanol) and the development of drug …

To fully make use of the synergism between paclitaxel and curcumin (CUR) in cancer
treatment, carrier made from CUR derivative was synthesized and used to deliver paclitaxel …

The purpose of this study was to develop paclitaxel (PTX) formulations with solid dispersion
(SD) and micelles (M) in order to improve solubility and oral absorption in rats. In addition …

Purpose Paclitaxel (PTX) has been widely utilized for the treatment of breast cancer.
However, drawbacks, such as poor aqueous solubility, rapid blood clearance and severe …

The aim of this study was to explore the solubilization efficacy of octenylsuccinate
hydroxypropyl phytoglycogen (OHPP), an amphiphilic dendrimer-like biopolymer, in …

Saccharides have been applied as a water-soluble matrix for dispersing hydrophobic drugs
homogeneously without the need to use surfactants in amorphous solid dispersions (ASD) …

In this work, paclitaxel was loaded into porous starch in the form of nanoparticles (PNPS),
and the properties of PNPS were investigated by using raw paclitaxel and the system of …

Paclitaxel (PTX), one of the most potent anticancer agents, has showed a remarkable activity
against varieties of tumors. However, the bioavailability of PTX is quite low due to its poor …