Validation of the nickel biotic ligand model for locally relevant species in Australian freshwaters

A Peters, G Merrington, C Schlekat… - Environmental …, 2018 - Wiley Online Library
Australian freshwaters have relatively low water hardness and different calcium (Ca) to
magnesium (Mg) ratios compared with those in Europe. The hardness values of a …

A review of water quality factors that affect nickel bioavailability to aquatic organisms: Refinement of the biotic ligand model for nickel in acute and chronic exposures

RC Santore, K Croteau, AC Ryan… - Environmental …, 2021 - Wiley Online Library
A review of nickel (Ni) toxicity to aquatic organisms was conducted to determine the primary
water quality factors that affect Ni toxicity and to provide information for the development and …

Nickel speciation and ecotoxicity in European natural surface waters: development, refinement and validation of bioavailability models

K De Schamphelaere, L Van Laer, N Deleebeeck… - 2006 - biblio.ugent.be
The accurate prediction of Ni ecotoxicity in natural surface water with bioavailability models
such as the biotic ligand model (BLM) depends on how well these models can predict both …

Refinement and cross‐validation of nickel bioavailability in PNEC‐Pro, a regulatory tool for site‐specific risk assessment of metals in surface water

AJ Verschoor, MG Vijver… - … Toxicology and Chemistry, 2017 - Wiley Online Library
Abstract The European Water Framework Directive prescribes that the environmental quality
standards for nickel in surface waters should be based on bioavailable concentrations …

The mechanisms of nickel toxicity in aquatic environments: An adverse outcome pathway analysis

KV Brix, CE Schlekat… - … toxicology and chemistry, 2017 - Wiley Online Library
Current ecological risk assessment and water quality regulations for nickel (Ni) use
mechanistically based, predictive tools such as biotic ligand models (BLMs). However …

Does the scientific underpinning of regulatory tools to estimate bioavailability of nickel in freshwaters matter? The European‐wide environmental quality standard for …

A Peters, CE Schlekat… - … Toxicology and Chemistry, 2016 - Wiley Online Library
A bioavailability‐based environmental quality standard (EQS) was established for nickel in
freshwaters under the European Union's Water Framework Directive. Bioavailability …

Empirical bioavailability corrections for nickel in freshwaters for Australia and New Zealand water quality guideline development

A Peters, G Merrington, J Stauber… - Environmental …, 2021 - Wiley Online Library
Bioavailability‐based approaches have been developed for the regulation of metals in
freshwaters in several countries. Empirical multiple linear regression (MLR) models have …

Comparison of multiple linear regression and biotic ligand models to predict the toxicity of nickel to aquatic freshwater organisms

K Croteau, AC Ryan, R Santore… - Environmental …, 2021 - Wiley Online Library
Toxicity‐modifying factors can be modeled either empirically with linear regression models
or mechanistically, such as with the biotic ligand model (BLM). The primary factors affecting …

Validation of nickel bioavailability models for algae, invertebrates, and fish in Chinese surface waters

J He, C Wang, CE Schlekat, F Wu… - Environmental …, 2023 - Wiley Online Library
Nickel (Ni) is used primarily in the production of alloys like stainless steel and is increasingly
being used in the production of batteries for the electric vehicle market. Exposure of Ni to …

Application of bioavailability models to derive chronic guideline values for nickel in freshwaters of Australia and New Zealand

J Stauber, L Golding, A Peters… - Environmental …, 2021 - Wiley Online Library
There has been an increased emphasis on incorporating bioavailability‐based approaches
into freshwater guideline value derivations for metals in the Australian and New Zealand …