Kv7 channels are voltage-gated potassium channels encoded by KCNQ genes that have a
considerable physiological impact in many cell types. This reliance upon Kv7 channels for …

Background: Neuronal KCNQ channels (KV7. 2-5) represent attractive targets for the
development of therapeutics for chronic and neuropathic pain, migraine, epilepsy and other …

Abstract Kv7. 1-Kv7. 5 (KCNQ1–5) K+ channels are voltage-gated K+ channels with major
roles in neurons, muscle cells and epithelia where they underlie physiologically important …

Kv7 channels are unique among K+ channels, since four out of the five channel subtypes
have well-documented roles in the development of human diseases. They have distinct …

KV 7 voltage-gated potassium channels, encoded by the KCNQ gene family, have caught
increasing interest of the scientific community for their important physiological roles, which …

Voltage-gated Kv7 (or KCNQ) channels play a pivotal role in controlling membrane
excitability. Like typical voltage-gated ion channels, Kv7 channels undergo a closed-to-open …

Potassium channels play an important role in electrical signaling of excitable cells such as
neurons, cardiac myocytes, and vascular smooth muscle cells (VSMCs). In particular, the …

Kv7 channels (KCNQ) represent a family of voltage‐gated K+ channels which plays a
prominent role in brain and cardiac excitability. Their physiological importance is …

Background: The Kv7 (KCNQ) subfamily of voltage-gated potassium channels consists of 5
members (Kv7. 1-5) each showing characteristic tissue distribution and physiological roles …

Kv7 potassium channels regulate excitability in neuronal, sensory, and muscular cells. Here,
we describe their molecular architecture, physiological roles, and involvement in genetically …