Regulatory B (B10) cells can control several inflammatory diseases, including allergies;
however, the origin of peripheral B10 cells is not fully understood, and the involvement of …

Background The mechanisms through which allergies can be inhibited after preconception
immunization with allergens are not fully understood. We aimed to evaluate whether …

Background Regulatory B cells have been identified that strongly reduce allergic and auto‐
immune inflammation in experimental models by producing IL‐10. Recently, several human …

Background IL-17-producing B cells can be identified in both mice and human and were
named B17 cells. The role of B17 cells still needs to be elucidated and its inflammatory or …

The potential of IgG antibodies as allergy regulators has been discussed for decades and
was brought to light that anti-allergen IgG is related to allergy inhibition in children during the …

Background The precise mechanism involved in the acquisition of the IL‐17+ profile of γδT
cells, the ligands responsible for this change, and whether this default is acquired during …

In this issue of the Journal of Allergy and Clinical Immunology, Amu and colleagues
demonstrate a significant role for interleukin-10 (IL-10)-producing regulatory B (Breg) cells …

B cells are essentially described for their capacity to produce antibodies ensuring anti‐
infectious immunity or deleterious responses in the case of autoimmunity or allergy …

Background Cytokines play an important role in mediating immunoglobulin switch, the
secretion of protective mucosal immunoglobulins, and the development of allergic diseases …

BACKGROUND: IL-10–producing regulatory B cells suppress immune responses, and lack
of these cells leads to exacerbated symptoms in mouse models of chronic inflammation …