Toxoplasma gondii is an obligate intracellular parasite belonging to the phylum
Apicomplexa that infects all warm-blooded animals, including humans. T. gondii can …

Apicomplexan parasites have complex metabolic networks that coordinate acquisition of
metabolites by de novo synthesis and by scavenging from the host. Toxoplasma gondii has …

The obligate intracellular parasite Toxoplasma gondii is auxotrophic for several key
metabolites and must scavenge these from the host. It is unclear how T. gondii manipulates …

Toxoplasma gondii is a widespread intracellular pathogen infecting humans and a variety of
animals. Previous studies have shown that Toxoplasma uses glucose and glutamine as the …

To survive and proliferate in diverse host environments with varying nutrient availability, the
obligate intracellular parasite Toxoplasma gondii reprograms its metabolism. We have …

Toxoplasma gondii proliferates within host cell vacuoles where the parasite relies on host
carbon and nutrients for replication. To assess how T. gondii utilizes these resources, we …

Like any obligate intracellular pathogen, the parasite Toxoplasma gondii has lost its capacity
for living independently of another organism. Toxoplasma lacks many genes that encode for …

Toxoplasma gondii is a widespread protozoan parasite infecting nearly all warm-blooded
organisms. Asexual reproduction of the parasite within its host cells is achieved by …

Toxoplasma gondii is capable of actively invading almost any mammalian cell type including
phagocytes. Early events in phagocytic cells such as dendritic cells are not only key to …

Metabolic pathways underpin the growth and virulence of intracellular parasites and are
therefore promising antiparasitic targets. The pentose phosphate pathway (PPP) is vital in …