Epigenetics: a molecular link between environmental factors and type 2 diabetes
Although obesity, reduced physical activity, and aging increase susceptibility to type 2
diabetes, many people exposed to these risk factors do not develop the disease. Recent …
diabetes, many people exposed to these risk factors do not develop the disease. Recent …
Genetics of type 2 diabetes
A Stančáková, M Laakso - Novelties in Diabetes, 2016 - karger.com
Genetic and environmental factors as well as their interactions contribute to the
pathogenesis of type 2 diabetes. Linkage analysis, candidate gene approaches, genome …
pathogenesis of type 2 diabetes. Linkage analysis, candidate gene approaches, genome …
Do gene–environment interactions have implications for the precision prevention of type 2 diabetes?
TIA Sørensen, S Metz, TO Kilpeläinen - Diabetologia, 2022 - Springer
The past decades have seen a rapid global rise in the incidence of type 2 diabetes. This
surge has been driven by diabetogenic environmental changes that may act together with a …
surge has been driven by diabetogenic environmental changes that may act together with a …
Environmental and genetic contributions to diabetes
J Tremblay, P Hamet - Metabolism, 2019 - Elsevier
Diabetes mellitus (DM) is a heterogeneous group of disorders characterized by persistent
hyperglycemia. Its two most common forms are type 1 diabetes (T1D) and type 2 diabetes …
hyperglycemia. Its two most common forms are type 1 diabetes (T1D) and type 2 diabetes …
Epigenetics and epigenomics: implications for diabetes and obesity
The American Diabetes Association convened a research symposium,“Epigenetics and
Epigenomics: Implications for Diabetes and Obesity” on 17–19 November 2017 …
Epigenomics: Implications for Diabetes and Obesity” on 17–19 November 2017 …
Gene-environment interactions in the development of type 2 diabetes: recent progress and continuing challenges
MC Cornelis, FB Hu - Annual review of nutrition, 2012 - annualreviews.org
Type 2 diabetes (T2D) is thought to arise from the complex interplay of both genetic and
environmental factors. Since the advent of genome-wide association studies (GWAS), we …
environmental factors. Since the advent of genome-wide association studies (GWAS), we …
Gene× environment interactions in type 2 diabetes
PW Franks - Current diabetes reports, 2011 - Springer
People vary genetically in their susceptibility to the effects of environmental risk factors for
many diseases. Genetic variation also underlies the extent to which people respond …
many diseases. Genetic variation also underlies the extent to which people respond …
Genes, environment, and interactions in prevention of type 2 diabetes: a focus on physical activity and lifestyle changes
Type 2 diabetes is one of the fastest growing public health problems worldwide. Both
environmental (eg physical activity, obesity, and diet) and genetic factors are involved in the …
environmental (eg physical activity, obesity, and diet) and genetic factors are involved in the …
Systematic identification of interaction effects between genome-and environment-wide associations in type 2 diabetes mellitus
Diseases such as type 2 diabetes (T2D) result from environmental and genetic factors, and
risk varies considerably in the population. T2D-related genetic loci discovered to date …
risk varies considerably in the population. T2D-related genetic loci discovered to date …
[引用][C] Environmental risk factors in human type 1 diabetes—an epidemiological perspective
G Dahlquist - Diabetes/metabolism reviews, 1995 - Wiley Online Library
The strong contribution of non-genetic factors to the aetiology of type 1 diabetes was first
proven by findings of only a 50% concordance rate of the disease among monozygotic …
proven by findings of only a 50% concordance rate of the disease among monozygotic …