Objectives Opiorphin is an analgesic peptide released by salivary glands and capsaicin an
agonist of TRPV1 receptors eliciting burning sensations. The primary objective of this study …

Objectives Opiorphin is a pentapeptide isolated from human saliva that suppresses pain
from chemically induced inflammation and acute physical pain. Burning mouth syndrome …

Background: Burning mouth syndrome (BMS) is characterized by intense burning sensation
of the tongue or other regions of the oral mucosa with no known medical or dental cause …

Aims: To assess the effect of topical application of capsaicin to the tongue as a surrogate
model of burning mouth syndrome (BMS) on somatosensory sensitivity by using a …

Objectives: Opiorphin is an enkephalinase inhibitor which suppresses pain by acting on the
opioid system. The levels of opiorphin in plasma and saliva have shown to vary in patients …

Abstract Objectives Idiopathic Burning mouth syndrome (iBMS) is a poorly understood
affection characterized by persistent pain in the oral cavity without any clinical or biological …

The aim of this meta-analysis was to answer the following question:“Are there any
differences in opiorphin biomarker concentrations between different orofacial conditions and …

Objectives Opiorphin is a recently discovered peptide shown to inhibit the enkephalin-
degrading enzymes and prolong the effects of enkephalins. Although opiorphin is found in …

This study was designed to investigate the effect of surrogate orofacial pain models on the
quantitative sensory testing (QST) profile in healthy participants. Capsaicin, menthol, or …

Objective Opiorphin is a pentapeptide secreted in saliva and has a strong analgesic effect.
Salivary opiorphin has been shown to increase in orofacial pain and may act as a pain …