A call for a Human Exposome Project

T Hartung - ALTEX-Alternatives to animal experimentation, 2023 - altex.org
Four decades of the Human Genome Project and its consequences have shown how the
entrepreneurial state, through significant investment into science, can drive scientific …

The nature of nurture: refining the definition of the exposome

GW Miller, DP Jones - Toxicological sciences, 2014 - academic.oup.com
Historical debates concerning human biology and behavior have frequently focused on
contributions of nature, ie, the inherited characteristics with which we are born, and nurture …

What is new about the exposome? Exploring scientific change in contemporary epidemiology

S Canali - International Journal of Environmental Research and …, 2020 - mdpi.com
In this commentary, I discuss the scientific changes brought by the exposome, asking what is
new about this approach and line of research. I place the exposome in a historical …

Implications of the exposome for exposure science

SM Rappaport - Journal of exposure science & environmental …, 2011 - nature.com
During the 1920s, the forerunners of exposure science collaborated with health
professionals to investigate the causes of occupational diseases. With the birth of US …

The exposome and health: Where chemistry meets biology

R Vermeulen, EL Schymanski, AL Barabási, GW Miller - Science, 2020 - science.org
Despite extensive evidence showing that exposure to specific chemicals can lead to
disease, current research approaches and regulatory policies fail to address the chemical …

Exposure science and the exposome: an opportunity for coherence in the environmental health sciences

PJ Lioy, SM Rappaport - Environmental health perspectives, 2011 - ehp.niehs.nih.gov
The field of exposure science began with qualitative observations and quantitative
measurements of air contaminants to aid our under standing of exposure–disease …

[HTML][HTML] Supporting and implementing the beneficial parts of the exposome: The environment can be the problem, but it can also be the solution

O Hahad, S Al-Kindi, J Lelieveld, T Münzel… - International journal of …, 2024 - Elsevier
Abstract In 2005, Christopher P. Wild introduced the exposome concept, encompassing the
biochemical changes in the organism in response to the totality of all environmental …

[图书][B] The exposome: A primer

GW Miller - 2013 - books.google.com
The Exposome: A Primer is the first book dedicated to exposomics, detailing the purpose
and scope of this emerging field of study, its practical applications and how it complements a …

Tackling the complexity of the exposome: considerations from the gunma university initiative for advanced research (GIAR) exposome symposium

P Zhang, M Arora, R Chaleckis, T Isobe, M Jain… - 2019 - mdpi.com
The attempt to describe complex diseases by solely genetic determination has not been
successful. There is increasing recognition that the development of disease is often a …

The exposome: from concept to utility

CP Wild - International journal of epidemiology, 2012 - academic.oup.com
The concept of the exposome was developed to draw attention to the critical need for more
complete environmental exposure assessment in epidemiological studies; 1–4 environment …