Lost but not least—novel insights into progesterone receptor loss in estrogen receptor-positive breast cancer
Simple Summary Most breast cancers co-express estrogen receptor α (ERα) and
progesterone receptor (PgR). These cancers are sensitive to endocrine therapy and, in …
progesterone receptor (PgR). These cancers are sensitive to endocrine therapy and, in …
Biology of progesterone receptor loss in breast cancer and its implications for endocrine therapy
The response to endocrine therapy in breast cancer correlates with estrogen receptor (ER)
and progesterone receptor (PR) status. ER-positive/PR-negative breast cancers respond …
and progesterone receptor (PR) status. ER-positive/PR-negative breast cancers respond …
Estrogen receptor-negative progesterone receptor-positive breast cancer–“Nobody's land “or just an artifact?
M Kunc, W Biernat, E Senkus-Konefka - Cancer treatment reviews, 2018 - Elsevier
The estrogen receptor α (ER) and the progesterone receptor (PgR) are one of the most
important prognostic and predictive immunohistochemical markers in breast cancer. Breast …
important prognostic and predictive immunohistochemical markers in breast cancer. Breast …
Progesterone Receptor Loss Correlates with Human Epidermal Growth Factor Receptor 2 Overexpression in Estrogen Receptor–Positive Breast Cancer
HJ Kim, X Cui, SG Hilsenbeck, AV Lee - Clinical cancer research, 2006 - AACR
Response to endocrine therapy in breast cancer correlates with estrogen receptor (ER) and
progesterone receptor (PR) status. It was originally hypothesized that the ability of PR to …
progesterone receptor (PR) status. It was originally hypothesized that the ability of PR to …
Molecular profiles of progesterone receptor loss in human breast tumors
CJ Creighton, C Kent Osborne, MJ van de Vijver… - Breast cancer research …, 2009 - Springer
Background Patient prognosis and response to endocrine therapy in breast cancer correlate
with protein expression of both estrogen receptor (ER) and progesterone receptor (PR), with …
with protein expression of both estrogen receptor (ER) and progesterone receptor (PR), with …
Outcomes of estrogen receptor negative and progesterone receptor positive breast cancer
M Chan, MC Chang, R González, B Lategan… - PloS one, 2015 - journals.plos.org
Purpose To describe the clinical features and outcomes of estrogen receptor negative (ER-)
and progesterone receptor positive (PgR+) breast cancer. Methods We retrospectively …
and progesterone receptor positive (PgR+) breast cancer. Methods We retrospectively …
Characterization of estrogen receptor-low-positive breast cancer
F Fei, GP Siegal, S Wei - Breast cancer research and treatment, 2021 - Springer
Purpose The biology of breast cancer with a low expression level (1–10%) of estrogen
receptor (ER) remains a matter of confusion. The recent American Society of …
receptor (ER) remains a matter of confusion. The recent American Society of …
Characterizing clinicopathologic features of estrogen receptor-positive/progesterone receptor-negative breast cancers
F Fei, GP Siegal, S Wei - Clinical breast cancer, 2022 - Elsevier
Background While most estrogen receptor-positive (ER+) breast cancers express
progesterone receptor (PR), a small subset of tumors exhibits an ER+/PR-phenotype despite …
progesterone receptor (PR), a small subset of tumors exhibits an ER+/PR-phenotype despite …
The impact of progesterone receptor negativity on oncological outcomes in oestrogen-receptor-positive breast cancer
Background Oestrogen receptor (ER) status provides invaluable prognostic and therapeutic
information in breast cancer (BC). When clinical decision making is driven by ER status, the …
information in breast cancer (BC). When clinical decision making is driven by ER status, the …
[HTML][HTML] High expression of progesterone receptor may be an adverse prognostic factor in oestrogen receptor-negative/progesterone receptor-positive breast cancer …
Summary Oestrogen receptor (ER)-negative (–) progesterone receptor (PgR)-positive (+) is
the least common combination of steroid receptor expression observed in breast cancer …
the least common combination of steroid receptor expression observed in breast cancer …
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