Lost but not least—novel insights into progesterone receptor loss in estrogen receptor-positive breast cancer

M Kunc, M Popęda, W Biernat, E Senkus - Cancers, 2021 - mdpi.com
Simple Summary Most breast cancers co-express estrogen receptor α (ERα) and
progesterone receptor (PgR). These cancers are sensitive to endocrine therapy and, in …

Biology of progesterone receptor loss in breast cancer and its implications for endocrine therapy

X Cui, R Schiff, G Arpino, CK Osborne… - Journal of clinical …, 2005 - ascopubs.org
The response to endocrine therapy in breast cancer correlates with estrogen receptor (ER)
and progesterone receptor (PR) status. ER-positive/PR-negative breast cancers respond …

Estrogen receptor-negative progesterone receptor-positive breast cancer–“Nobody's land “or just an artifact?

M Kunc, W Biernat, E Senkus-Konefka - Cancer treatment reviews, 2018 - Elsevier
The estrogen receptor α (ER) and the progesterone receptor (PgR) are one of the most
important prognostic and predictive immunohistochemical markers in breast cancer. Breast …

Progesterone Receptor Loss Correlates with Human Epidermal Growth Factor Receptor 2 Overexpression in Estrogen Receptor–Positive Breast Cancer

HJ Kim, X Cui, SG Hilsenbeck, AV Lee - Clinical cancer research, 2006 - AACR
Response to endocrine therapy in breast cancer correlates with estrogen receptor (ER) and
progesterone receptor (PR) status. It was originally hypothesized that the ability of PR to …

Molecular profiles of progesterone receptor loss in human breast tumors

CJ Creighton, C Kent Osborne, MJ van de Vijver… - Breast cancer research …, 2009 - Springer
Background Patient prognosis and response to endocrine therapy in breast cancer correlate
with protein expression of both estrogen receptor (ER) and progesterone receptor (PR), with …

Outcomes of estrogen receptor negative and progesterone receptor positive breast cancer

M Chan, MC Chang, R González, B Lategan… - PloS one, 2015 - journals.plos.org
Purpose To describe the clinical features and outcomes of estrogen receptor negative (ER-)
and progesterone receptor positive (PgR+) breast cancer. Methods We retrospectively …

Characterization of estrogen receptor-low-positive breast cancer

F Fei, GP Siegal, S Wei - Breast cancer research and treatment, 2021 - Springer
Purpose The biology of breast cancer with a low expression level (1–10%) of estrogen
receptor (ER) remains a matter of confusion. The recent American Society of …

Characterizing clinicopathologic features of estrogen receptor-positive/progesterone receptor-negative breast cancers

F Fei, GP Siegal, S Wei - Clinical breast cancer, 2022 - Elsevier
Background While most estrogen receptor-positive (ER+) breast cancers express
progesterone receptor (PR), a small subset of tumors exhibits an ER+/PR-phenotype despite …

The impact of progesterone receptor negativity on oncological outcomes in oestrogen-receptor-positive breast cancer

MG Davey, ÉJ Ryan, PJ Folan, N O'Halloran… - BJS open, 2021 - academic.oup.com
Background Oestrogen receptor (ER) status provides invaluable prognostic and therapeutic
information in breast cancer (BC). When clinical decision making is driven by ER status, the …

[HTML][HTML] High expression of progesterone receptor may be an adverse prognostic factor in oestrogen receptor-negative/progesterone receptor-positive breast cancer …

M Kunc, R Pęksa, G Cserni, E Iżycka-Świeszewska… - Pathology, 2022 - Elsevier
Summary Oestrogen receptor (ER)-negative (–) progesterone receptor (PgR)-positive (+) is
the least common combination of steroid receptor expression observed in breast cancer …